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Efficacy and Safety of Intraoperative Hyperthermic Intraperitoneal Chemotherapy for Locally Advanced Colon Cancer: A Phase 3 Randomized Clinical Trial.局部进展期结肠癌术中腹腔热灌注化疗的疗效和安全性：一项 3 期随机临床试验。
JAMA Surg. 2023 Jul 1;158(7):683-691. doi: 10.1001/jamasurg.2023.0662.
2
Feasibility Study of a Network Meta-Analysis and Unanchored Population-Adjusted Indirect Treatment Comparison of Niraparib, Olaparib, and Bevacizumab as Maintenance Therapies in Patients with Newly Diagnosed Advanced Ovarian Cancer.尼拉帕利、奥拉帕利和贝伐单抗作为新诊断晚期卵巢癌患者维持治疗的网状Meta分析及非锚定人群校正间接治疗比较的可行性研究
Cancers (Basel). 2022 Mar 2;14(5):1285. doi: 10.3390/cancers14051285.
3
Nivolumab plus chemotherapy versus placebo plus chemotherapy in patients with HER2-negative, untreated, unresectable advanced or recurrent gastric or gastro-oesophageal junction cancer (ATTRACTION-4): a randomised, multicentre, double-blind, placebo-controlled, phase 3 trial.纳武利尤单抗联合化疗对比安慰剂联合化疗用于治疗人表皮生长因子受体 2（HER2）阴性、未经治疗、不可切除的晚期或复发性胃或胃食管结合部腺癌患者（ATTRACTION-4）：一项随机、多中心、双盲、安慰剂对照、3 期临床试验。
Lancet Oncol. 2022 Feb;23(2):234-247. doi: 10.1016/S1470-2045(21)00692-6. Epub 2022 Jan 11.
4
Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy versus cytoreductive surgery alone for colorectal peritoneal metastases (PRODIGE 7): a multicentre, randomised, open-label, phase 3 trial.细胞减灭术联合腹腔热灌注化疗与单纯细胞减灭术治疗结直肠腹膜转移瘤（PRODIGE 7）：一项多中心、随机、开放标签、3 期临床试验。
Lancet Oncol. 2021 Feb;22(2):256-266. doi: 10.1016/S1470-2045(20)30599-4. Epub 2021 Jan 18.
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Second-look surgery plus hyperthermic intraperitoneal chemotherapy versus surveillance in patients at high risk of developing colorectal peritoneal metastases (PROPHYLOCHIP-PRODIGE 15): a randomised, phase 3 study.二期手术加腹腔内热灌注化疗与监测在有发生结直肠腹膜转移高危患者中的对比（PROPHYLOCHIP-PRODIGE 15）：一项随机、3 期研究。
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Adjuvant hyperthermic intraperitoneal chemotherapy in patients with locally advanced colon cancer (COLOPEC): a multicentre, open-label, randomised trial.局部晚期结肠癌患者的辅助腹腔内热化疗（COLOPEC）：一项多中心、开放标签、随机试验。
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Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: protocol of a multicentre, open-label, parallel-group, phase II-III, randomised, superiority study (CAIRO6).围手术期全身治疗联合细胞减灭术和 HIPEC 对比单纯 HIPEC upfront 细胞减灭术治疗孤立可切除结直肠腹膜转移瘤：一项多中心、开放标签、平行组、Ⅱ-Ⅲ 期、随机、优效性研究（CAIRO6）方案。
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腹膜转移：从黯淡前景到令人鼓舞的现状及充满希望的未来的演变

Peritoneal Metastases: Evolution from a Dark Horizon to an Encouraging Present and a Promising Future.

作者信息

Diez-Alonso Manuel, San-Juan Alberto, Ortega Miguel Angel, Gutiérrez-Calvo Alberto

机构信息

General Surgery Service, University Hospital Príncipe de Asturias, 28820 Alcalá de Henares, Spain.

Medical Oncology Service, University Hospital Príncipe de Asturias, 28820 Alcalá de Henares, Spain.

出版信息

J Clin Med. 2023 Dec 6;12(24):7536. doi: 10.3390/jcm12247536.

DOI:10.3390/jcm12247536
PMID:38137604
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10743464/
Abstract

Peritoneal metastasis (PM) is the primary pattern of metastasis for primary tumours of the appendix, ovary, and peritoneal mesothelioma [...].

摘要

腹膜转移（PM）是阑尾、卵巢和腹膜间皮瘤等原发性肿瘤转移的主要模式[……]