Dell'Aversana Serena, Ascione Raffaele, Vitale Raffaella Antonia, Cavaliere Fabrizia, Porcaro Piercarmine, Basile Luigi, Napolitano Giovanni, Boccalatte Marco, Sibilio Gerolamo, Esposito Giovanni, Franzone Anna, Di Costanzo Giuseppe, Muscogiuri Giuseppe, Sironi Sandro, Cuocolo Renato, Cavaglià Enrico, Ponsiglione Andrea, Imbriaco Massimo
Department of Radiology, Santa Maria Delle Grazie Hospital, ASL Napoli 2 Nord, 80078 Pozzuoli, Italy.
Department of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, Italy.
J Clin Med. 2023 Dec 11;12(24):7615. doi: 10.3390/jcm12247615.
Coronary computed tomography angiography (CCTA) currently represents a robust imaging technique for the detection, quantification and characterization of coronary atherosclerosis. However, CCTA remains a challenging task requiring both high spatial and temporal resolution to provide motion-free images of the coronary arteries. Several CCTA features, such as low attenuation, positive remodeling, spotty calcification, napkin-ring and high pericoronary fat attenuation index have been proved as associated to high-risk plaques. This review aims to explore the role of CCTA in the characterization of high-risk atherosclerotic plaque and the recent advancements in CCTA technologies with a focus on radiomics plaque analysis.
冠状动脉计算机断层扫描血管造影(CCTA)目前是一种用于检测、量化和表征冠状动脉粥样硬化的强大成像技术。然而,CCTA仍然是一项具有挑战性的任务,需要高空间和时间分辨率才能提供冠状动脉的无运动图像。一些CCTA特征,如低衰减、正向重塑、斑点状钙化、餐巾环和高冠状动脉周围脂肪衰减指数,已被证明与高危斑块相关。本综述旨在探讨CCTA在高危动脉粥样硬化斑块表征中的作用以及CCTA技术的最新进展,重点是放射组学斑块分析。