Băieş Mihai-Horia, Cotuţiu Vlad-Dan, Spînu Marina, Mathe Attila, Cozma-Petruț Anamaria, Bocǎneţ Vlad I, Cozma Vasile
Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, 3-5 Mǎnǎştur Street, 400372 Cluj-Napoca, Romania.
Department of Infectious Diseases, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, 3-5 Mǎnǎştur Street, 400372 Cluj-Napoca, Romania.
Microorganisms. 2023 Dec 13;11(12):2980. doi: 10.3390/microorganisms11122980.
Internal parasitic diseases of swine constitute a major welfare and health concern in low-input livestock farming. Due to an increase in chemical resistance, phytotherapeutic remedies have become an alternative for the prophylaxis and therapy of digestive parasitosis, albeit few remedies have been subjected to scientific validation. Low-input swine farming in Romania has adopted the traditional use of phytotherapy for controlling pathogens in livestock. The current study aimed to assess the antiparasitic potential of and against digestive parasites of swine in two low-input farms. The fecal samples were collected from sows, fatteners, and weaners, and were tested using the following coproparasitological methods: centrifugal sedimentation, flotation (Willis, McMaster egg counting technique), Ziehl-Neelsen stain modified by Henricksen, modified Blagg method, and in vitro nematode larvae/protozoan oocyst cultures. Six species of digestive parasites were diagnosed, namely , , spp., , spp., and spp., in various combinations, dependent on the swine category. A dose of 140 mg/kg bw/day of and 100 mg/kg bw/day of powders administered for 10 consecutive days revealed a strong antiprotozoal and anthelmintic activity on the aforementioned parasites. The curative efficacy can be attributed to the presence of polyphenols, sterols, tocopherols, and methoxylated flavones. In conclusion, our results indicate that and are promising alternatives to the commercially available antiparasitics, enabling their use as natural antiparasitic products against gastrointestinal parasites in pigs.
猪的体内寄生虫病是低投入畜牧业中主要的福利和健康问题。由于化学抗性增加，植物疗法已成为预防和治疗消化寄生虫病的一种替代方法，尽管很少有疗法经过科学验证。罗马尼亚的低投入养猪业采用了植物疗法的传统用法来控制家畜中的病原体。本研究旨在评估[具体植物1]和[具体植物2]对两个低投入农场猪的消化寄生虫的抗寄生虫潜力。从母猪、育肥猪和断奶仔猪采集粪便样本，并使用以下粪便寄生虫学方法进行检测：离心沉淀法、浮选法（威利斯法、麦克马斯特虫卵计数技术）、亨里克森改良的齐尔-尼尔森染色法、改良布拉格法以及体外线虫幼虫/原生动物卵囊培养法。根据猪的类别，诊断出六种消化寄生虫，即[寄生虫1名称]、[寄生虫2名称]、[寄生虫3属名] spp.、[寄生虫4名称]、[寄生虫5属名] spp.和[寄生虫6名称] spp.，它们以不同组合出现。连续10天每天分别给予140 mg/kg体重的[具体植物1]粉末和100 mg/kg体重的[具体植物2]粉末，对上述寄生虫显示出很强的抗原虫和驱虫活性。这种治疗效果可归因于多酚、甾醇、生育酚和甲氧基黄酮的存在。总之，我们的结果表明，[具体植物1]和[具体植物2]有望成为市售抗寄生虫药物的替代品，能够用作对抗猪胃肠道寄生虫的天然抗寄生虫产品。
