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新冠病毒感染后双侧突发性感音神经性听力损失患者的人工耳蜗植入术

Cochlear Implantation in Patients with Bilateral Sudden Sensorineural Hearing Loss after COVID-19 Infection.

作者信息

Arsović Nenad, Jovanović Marija, Babac Snežana, Čvorović Ljiljana, Radivojević Nemanja, Arsović Konstantin

机构信息

Faculty of Medicine, University of Belgrade, 11000 Beograd, Serbia.

Institute for Otorhinolaryngology and Maxillofacial Surgery, Clinical Centre of Serbia, 11000 Beograd, Serbia.

出版信息

J Pers Med. 2023 Dec 14;13(12):1708. doi: 10.3390/jpm13121708.

DOI:10.3390/jpm13121708
PMID:38138935
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10745051/
Abstract

COVID-19 infection is associated with a variety of neurological manifestations. Since the inner ear is vulnerable to viruses, sensorineural hearing loss (SNHL) has been reported to occur following SARS-CoV-2 infection. We present here two cases of profound SNHL following SARS-CoV-2 infection. Pure-tone audiograms confirmed profound SNHL. The tympanogram and Auditory Brainstem Responses showed no abnormal symptoms. MRIs and CTs identified some changes but no significant anatomical nor physiological manifestations explaining the obvious cause for hearing loss. High doses of oral corticosteroids with additional conservative therapy were given with no therapeutic response, and therefore, cochlear implant surgery was performed. One case was bilaterally treated, and the other one received an implantation on one side. Both surgeries were carried out without intra- nor postoperative complications. Interestingly, in both cases, advanced fibrotic tissue was found during surgery. Both cases reported successful rehabilitation and are satisfied with their new sound perception following cochlear implantation.

摘要

新型冠状病毒肺炎(COVID-19)感染与多种神经学表现相关。由于内耳易受病毒侵害,据报道,感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)后会出现感音神经性听力损失(SNHL)。我们在此介绍两例SARS-CoV-2感染后出现严重SNHL的病例。纯音听力图证实为严重SNHL。鼓室图和听觉脑干反应未显示异常症状。磁共振成像(MRI)和计算机断层扫描(CT)发现了一些变化,但没有明显的解剖学或生理学表现来解释听力损失的明显原因。给予高剂量口服糖皮质激素并辅以其他保守治疗,但无治疗反应,因此进行了人工耳蜗植入手术。1例为双侧治疗,另1例为单侧植入。两台手术均未出现术中及术后并发症。有趣的是,在两例手术中均发现了晚期纤维化组织。两例均报告康复成功,并对人工耳蜗植入后的新声音感知感到满意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b259/10745051/cc6ce3702336/jpm-13-01708-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b259/10745051/f012dcf6e1f8/jpm-13-01708-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b259/10745051/6c645c9f4a2a/jpm-13-01708-g002a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b259/10745051/e64a91834e0e/jpm-13-01708-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b259/10745051/53f3cd431f32/jpm-13-01708-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b259/10745051/cc6ce3702336/jpm-13-01708-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b259/10745051/f012dcf6e1f8/jpm-13-01708-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b259/10745051/6c645c9f4a2a/jpm-13-01708-g002a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b259/10745051/e64a91834e0e/jpm-13-01708-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b259/10745051/53f3cd431f32/jpm-13-01708-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b259/10745051/cc6ce3702336/jpm-13-01708-g005.jpg

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Hearing loss and COVID-19: an umbrella review.听力损失与 COVID-19:伞式综述。
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Sudden Sensorineural Hearing Loss in the COVID-19 Pandemic: A Systematic Review and Meta-Analysis.
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