Tran Thanh, Igudesman Daria, Burger Kyle, Crandell Jamie, Maahs David M, Seid Michael, Mayer-Davis Elizabeth J
Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Translational Research Institute, AdventHealth, Orlando, FL, USA.
Diabetes Res Clin Pract. 2024 Jan;207:111070. doi: 10.1016/j.diabres.2023.111070. Epub 2023 Dec 22.
Estimate associations between select eating behaviors and estimated body fat percentage (eBFP) and explore effect modification by sex among adolescents with type 1 diabetes (T1D).
This analysis included 257 adolescents (mean age 14.9 ± 1.14 years; 49.8 % female) with baseline hemoglobin A1c (HbA1c) between 8 and 13 % (64 mmol/mol-119 mmol/mol) from a randomized trial designed to improve glycemia. Eating behaviors and eBFP were determined from surveys and validated equations respectively. Linear mixed models were used to estimate associations. Effect modification was assessed via stratified plots, stratified associations, and interaction terms.
Disordered eating, dietary restraint, and eBFP were significantly higher among females while external eating was higher among males. Disordered eating (β: 0.49, 95 %CI: 0.24, 0.73, p = 0.0001) and restraint (β: 1.11, 95 %CI: 0.29, 1.92, p = 0.0081) were positively associated with eBFP while external eating was not (β: -0.19, 95 %CI: -0.470, 0.096, p = 0.20). Interactions with sex were not significant (p-value range: 0.28-0.64).
Disordered eating and dietary restraint were positively associated with eBFP, highlighting the potential salience of these eating behaviors to cardiometabolic risk for both female and male adolescents. Prospective studies should investigate whether these eating behaviors predict eBFP longitudinally to inform obesity prevention strategies in T1D.
评估特定饮食行为与估计体脂百分比(eBFP)之间的关联,并探讨1型糖尿病(T1D)青少年中性别对这种关联的影响。
该分析纳入了257名青少年(平均年龄14.9±1.14岁;49.8%为女性),他们来自一项旨在改善血糖水平的随机试验,基线糖化血红蛋白(HbA1c)在8%至13%(64 mmol/mol - 119 mmol/mol)之间。饮食行为和eBFP分别通过调查和验证方程确定。使用线性混合模型估计关联。通过分层图、分层关联和交互项评估效应修正。
女性的饮食失调、饮食限制和eBFP显著更高,而男性的外在进食更高。饮食失调(β:0.49,95%CI:0.24,0.73,p = 0.0001)和饮食限制(β:1.11,95%CI:0.29,1.92,p = 0.0081)与eBFP呈正相关,而外在进食则不然(β:-0.19,95%CI:-0.470,0.096,p = 0.20)。与性别的交互作用不显著(p值范围:0.28 - 0.64)。结论:饮食失调和饮食限制与eBFP呈正相关,突出了这些饮食行为对男女青少年心脏代谢风险的潜在重要性。前瞻性研究应调查这些饮食行为是否能纵向预测eBFP,以为T1D的肥胖预防策略提供信息。