Department of Operational and Implementation Research, Regional Resource Hub-Health Technology Assessment, ICMR-National Institute for Research in Reproductive and Child Health, Mumbai, Maharashtra, India.
Indian J Med Res. 2023 Nov 1;158(5&6):483-493. doi: 10.4103/ijmr.ijmr_2471_22. Epub 2024 Jan 24.
The prong 2 of 4 prong strategy introduced by the World Health Organization aims at averting unintended pregnancies among people living with HIV (PLHIV). This systematic review aimed to generate evidence on the effectuality of facility-based interventions in improving uptake of modern and dual contraception, for reducing unmet family planning (FP) needs and unintended pregnancies among PLHIV.
Articles evaluating facility-based interventions to integrate human immunodeficiency virus (HIV) and FP published in English language were included. Eligible studies were identified from electronic and lateral search from three databases (PubMed, Cochrane Library and Web of Science) and grey literature. HIV care with no/minimal focus on FP was considered a comparator. Quality was assessed using design-appropriate tools. Descriptive analysis was presented in tables. Uptake of dual methods, unmet FP needs and unintended pregnancies were included in the meta-analysis to estimate pooled odds ratio (OR) with random effect model, P and I2 values.
The search yielded 2112 results. After excluding duplicates and unfit articles, 17 were found eligible for review and nine for meta-analysis. The pooled OR for uptake of dual contraception was 1.69 (1.14, 2.5) ( P =0.008; I2 =90%), for unmet FP needs was 0.58 (0487, 0.69) ( P <0.00001; I2 =0%) and for unintended pregnancies was 0.6 (0.32, 1.1) ( P =0.1, I2 =38%).
The results of this meta-analysis suggest that health facility-based interventions to integrate HIV and FP services do result in improved uptake of dual methods and reduce unmet need for contraception along with a protective trend on incidence of unintended pregnancies. Such facility-based integration would ensure universal access to effective contraception and facilitate in achieving Sustainable Development Goals that aim at ending epidemics like HIV.
世界卫生组织提出的四步策略的第二步旨在避免艾滋病毒感染者(PLHIV)发生意外怀孕。本系统评价旨在为基于设施的干预措施在提高现代和双重避孕措施的采用率、减少 PLHIV 未满足的计划生育(FP)需求和意外怀孕方面的效果提供证据。
纳入评估以基于设施的干预措施整合艾滋病毒(HIV)和 FP 的英文文章。从三个数据库(PubMed、Cochrane 图书馆和 Web of Science)和灰色文献中通过电子和横向搜索确定合格研究。将 HIV 护理中对 FP 关注较少或没有关注作为对照。使用适当的设计工具评估质量。描述性分析以表格形式呈现。将双重方法的采用率、未满足的 FP 需求和意外怀孕纳入荟萃分析,使用随机效应模型估计汇总优势比(OR),并计算 P 值和 I2 值。
搜索产生了 2112 个结果。排除重复和不适合的文章后,发现 17 篇文章符合审查条件,9 篇文章符合荟萃分析条件。双重避孕措施采用率的汇总 OR 为 1.69(1.14,2.5)( P =0.008;I2 =90%),未满足的 FP 需求为 0.58(0.487,0.69)( P <0.00001;I2 =0%),意外怀孕率为 0.6(0.32,1.1)( P =0.1,I2 =38%)。
荟萃分析的结果表明,基于卫生设施的整合 HIV 和 FP 服务的干预措施确实可以提高双重方法的采用率,减少避孕需求的未满足,同时对意外怀孕的发生率产生保护趋势。这种基于设施的整合将确保普遍获得有效的避孕措施,并有助于实现旨在结束艾滋病毒等流行病的可持续发展目标。