Livesey Leanda, DeGraves Fred, Allred Courtney, Boone Lindsey, Schumacher John
Department of Clinical Sciences, College of Veterinary Medicine, Tuskegee University, AL 36088 (Livesey, Allred).
Department of Agriculture and Food Science, Ogden College of Science and Engineering, Western Kentucky University, Bowling Green, KY 42101, DeGraves.
J Equine Vet Sci. 2024 Feb;133:104974. doi: 10.1016/j.jevs.2023.104974. Epub 2023 Dec 24.
This study aimed to determine the efficacy of instilling extract of the pitcher plant around the palmar digital nerves of horses to ameliorate digit pain causing lameness. Five mixed breed horses were recruited. Horses were determined to be lame because of pain in the distal portion of one or both thoracic limbs by a positive response to a basisesamoid nerve block using 2%^mepivacaine hydrochloride. Gait was evaluated pre- and post-nerve block at 30 min, 3, 7,14 and 21 days. At the 3-week evaluation, the basisesamoid nerve block was repeated using the extract, and the gait was evaluated at similar times. Lameness was evaluated objectively using a wireless, inertial, sensor-based, motion analysis system. The basisesamoid nerve block significantly ameliorated lameness at 30 min when gait was evaluated, but it had no significant effect on lameness after this time. The product containing extract of the pitcher plant had no significant effect on lameness when administered as a basisesamoid nerve block at any time. Extract of the pitcher plant administered adjacent to the medial and lateral palmar digital nerves (i.e., a basisesamoid nerve block) had no efficacy in ameliorating lameness in the distal portion of one or both thoracic limbs. Extract of the pitcher plant likely has no value for treating horses for chronic pain when administered as a regional nerve block.
本研究旨在确定将猪笼草提取物注入马的掌指神经周围以减轻导致跛行的蹄部疼痛的疗效。招募了5匹杂种马。通过对使用2%盐酸甲哌卡因进行的籽骨下神经阻滞呈阳性反应，确定马因一个或两个胸肢远端疼痛而跛行。在神经阻滞前以及神经阻滞后的30分钟、3天、7天、14天和21天对步态进行评估。在3周评估时，使用提取物重复进行籽骨下神经阻滞，并在相似时间评估步态。使用基于无线惯性传感器的运动分析系统客观评估跛行情况。在评估步态时，籽骨下神经阻滞在30分钟时显著改善了跛行，但在此之后对跛行没有显著影响。当作为籽骨下神经阻滞给药时，含有猪笼草提取物的产品在任何时候对跛行均无显著影响。将猪笼草提取物注入掌内侧和外侧指神经附近（即籽骨下神经阻滞）对改善一个或两个胸肢远端的跛行无效。当作为区域神经阻滞给药时，猪笼草提取物可能对治疗马匹慢性疼痛没有价值。
