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探索英国急性冠状动脉综合征患者的临床轨迹与连续护理:一项全面的横断面分析。

Exploring Clinical Trajectories and the Continuum of Care for Patients With Acute Coronary Syndrome in the United Kingdom: A Thorough Cross-Sectional Analysis.

作者信息

Zaki Hany A, Bashir Israr, Mahdy Ahmed, Abdurabu Mohammed, Khallafalla Hosam, Fayed Mohamed, Elsayed Wael Abdelrehem Elnabawy, Abdelrahim Mohammed Gafar, Basharat Kaleem, Salloum Wathek, Shaban Eman

机构信息

Emergency Medicine, Hamad Medical Corporation, Doha, QAT.

Cardiology, Al Jufairi Diagnosis and Treatment, Doha, QAT.

出版信息

Cureus. 2023 Nov 25;15(11):e49391. doi: 10.7759/cureus.49391. eCollection 2023 Nov.

Abstract

The United Kingdom (UK) has a sustainable healthcare system. Nonetheless, the burden of acute coronary syndrome (ACS) is still a significant challenge. A scarcity of literature primarily focuses on the continuum of care for ACS patients in the UK. Moreover, limited research studies highlight the clinical trajectories of ACS patients across the UK. Therefore, the current study was designed to explore clinical trajectories and the continuum of care for patients with ACS in the UK. Secondary data was obtained from the Myocardial Ischaemia National Audit Project (MINAP) database. The latest data available in the MINAP database was used. As our objective was to explore clinical trajectories and the continuum of care for patients, we retrieved data regarding the care received by ACS patients admitted to hospitals across the UK.  The data of 85574 ACS patients was retrieved. A large number (n=47035) of patients were estimated to be eligible for the angiogram; however, an angiogram was performed for 87.15% (n=40995) of eligible patients. Angioplasty within 72 hours of admission was required for most (n=26313) ACS patients. Nonetheless, angioplasty within 72 hours of admission was performed for 59.7% (n=15703) of the eligible patients. There was a significant difference (P<0.05) between different regions of the UK and the percentage of patients for whom angioplasty was performed within 72 hours of admission. Primary percutaneous coronary intervention (PCI) was performed for 23923 ACS patients, of which the door-to-balloon interval for 17590 (73.5%) patients was ≤60 minutes while the door-to-balloon interval for 3086 (12.9%) patients was ≤90 minutes. Out of the total 85574 ACS patients, 65959 (77.08%) patients were discharged on appropriate medications, while 19615 (22.92%) were transferred to another hospital or died there. A total of 75361 were eligible to be referred to cardiac rehabilitation settings. Nonetheless, 64518 (85.61%) were referred to cardiac rehabilitation. About 85000 patients were reported in the UK (England, Northern Ireland, Wales). Optimal care was provided to most patients in the UK. However, some patients received sub-optimal care, highlighting the disparity in the healthcare system. There is a need to explore further the factors that might be responsible for the sub-optimal care to the patients.

摘要

英国拥有可持续的医疗保健系统。尽管如此,急性冠状动脉综合征(ACS)的负担仍然是一项重大挑战。目前主要关注英国ACS患者连续护理的文献较少。此外,仅有有限的研究关注英国各地ACS患者的临床病程。因此,本研究旨在探讨英国ACS患者的临床病程及连续护理情况。我们从心肌缺血国家审计项目(MINAP)数据库中获取了二手数据,使用的是该数据库中可获取的最新数据。由于我们的目标是探究患者的临床病程及连续护理情况,因此检索了英国各地医院收治的ACS患者所接受护理的数据。共检索到85574例ACS患者的数据。估计大量患者(n = 47035)符合血管造影条件;然而,在符合条件的患者中,有87.15%(n = 40995)进行了血管造影。大多数ACS患者(n = 26313)需要在入院72小时内进行血管成形术;尽管如此,在符合条件的患者中,有59.7%(n = 15703)在入院72小时内进行了血管成形术。英国不同地区之间以及入院72小时内进行血管成形术的患者比例存在显著差异(P < 0.05)。23923例ACS患者接受了直接经皮冠状动脉介入治疗(PCI),其中17590例(73.5%)患者的门球时间≤60分钟,3086例(12.9%)患者的门球时间≤90分钟。在总共85574例ACS患者中,65959例(77.08%)患者出院时服用了适当药物,而19615例(22.92%)患者被转至其他医院或在那里死亡。共有75361例患者符合转至心脏康复机构的条件;尽管如此,其中64518例(85.61%)被转至心脏康复机构。英国(英格兰、北爱尔兰、威尔士)报告的患者约有85000例。英国大多数患者得到了最佳护理。然而,一些患者接受的护理未达最佳水平,这凸显了医疗保健系统中的差异。有必要进一步探究可能导致患者接受非最佳护理的因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07a7/10749670/2c52d40fa71c/cureus-0015-00000049391-i01.jpg

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