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地塞米松抑制试验无抑制状态:与抑郁综合征特定方面的关系。

DST nonsuppressor status: relationship to specific aspects of the depressive syndrome.

作者信息

Winokur G, Black D W, Nasrallah A

出版信息

Biol Psychiatry. 1987 Mar;22(3):360-8. doi: 10.1016/0006-3223(87)90153-3.

Abstract

Using a conservative definition of suppressor status in hospitalized depressives, we found a relationship between abnormal endocrine function and certain kinds of depressive symptoms, i.e., melancholic symptoms, delusions, and memory deficit. Normal suppressor status is related to an early age of onset, absence of delusions, absence of memory deficit, absence of melancholia symptoms, and a presence of a diagnosis of secondary depression or a family history of alcoholism in depressives. The data suggest the distinction between neurotic-reactive depression and endogenous depression. It is equally important to note that these specific symptoms and characteristics possibly are associated with suppressor status independently of each other.

摘要

采用对住院抑郁症患者抑制状态的保守定义,我们发现异常内分泌功能与某些类型的抑郁症状之间存在关联,即忧郁症状、妄想和记忆缺陷。正常抑制状态与发病年龄早、无妄想、无记忆缺陷、无忧郁症状以及抑郁症患者中存在继发性抑郁症诊断或酗酒家族史有关。这些数据表明了神经症反应性抑郁症和内源性抑郁症之间的区别。同样重要的是要注意,这些特定症状和特征可能彼此独立地与抑制状态相关。

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