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[给予全氟碳化合物乳剂后单核吞噬细胞系统的功能]

[Function of the mononuclear phagocyte system after administration of emulsions of perfluorinated carbon compounds].

作者信息

Vishnevetskiĭ F E, Golubev A M, Beloiartsev F F, Vasil'ev A E, Pokrovskiĭ Iu E

出版信息

Biull Eksp Biol Med. 1987 Feb;103(2):232-6.

PMID:3814812
Abstract

Morpho-functional characteristics of mononuclear phagocyte system (MPS) have been studied in experimental animals upon the infusions of perfluorocarbon (PFC) emulsions. It has been established that the infusion of high doses of PFC emulsions following massive hemorrhage causes the reduction in the histoenzymatic activity in MPS of PFC-accumulating organs. Low doses of PFC emulsions increase histochemical activity in PFC-containing macrophages, suggesting a stimulating effect of PFC emulsions on MPS.

摘要

在实验动物中,通过输注全氟碳(PFC)乳剂,对单核吞噬细胞系统(MPS)的形态功能特征进行了研究。已证实,在大量出血后输注高剂量的PFC乳剂会导致PFC蓄积器官的MPS中组织酶活性降低。低剂量的PFC乳剂可增加含PFC巨噬细胞的组织化学活性,表明PFC乳剂对MPS有刺激作用。

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