Marks J, Harding K G, Hughes L E
Br J Surg. 1987 Feb;74(2):95-7. doi: 10.1002/bjs.1800740207.
The significance of staphylococcal infection has been studied prospectively in 250 wounds healing by open granulation. In a series of 50 axillary skin excisions, 17 became infected with Staphylococcus aureus with consequent pain and delay in healing. The infections responded well to Fucidin ointment. Nasal carriers of the organism may be especially liable to this complication. In contrast, although S. aureus was not infrequently found in deep granulating wounds, there was no clear evidence of harm resulting in the 50 laparotomy wounds and 150 pilonidal sinus excisions studied. The susceptibility of superficial wounds to the infection is ascribed to friction from dressings. Deep granulating wounds are occasionally affected similarly when the cavity has filled.
我们对250例通过开放肉芽形成愈合的伤口进行了前瞻性研究，以探讨葡萄球菌感染的意义。在一系列50例腋窝皮肤切除术中，17例感染了金黄色葡萄球菌，导致疼痛和愈合延迟。这些感染对梭链孢酸钠软膏反应良好。该病菌的鼻腔携带者可能特别容易出现这种并发症。相比之下，尽管在深部肉芽伤口中经常发现金黄色葡萄球菌，但在研究的50例剖腹手术伤口和150例藏毛窦切除术中，没有明显证据表明其造成危害。浅表伤口对感染的易感性归因于敷料的摩擦。当腔隙填满时，深部肉芽伤口偶尔也会受到类似影响。
