Frańková V, Chýle M, Duniewicz M, Marhoul Z, Kolman J M, Mancal P
J Hyg Epidemiol Microbiol Immunol. 1978;22(4):502-10.
The indirect IF technique, using suspensions of TBE virus infected and uninfected PS cells as antigen-containing substrate, furnishes a rapid and practical test making possible the detection of specific IgM class serum antibodies in the initial stage of clinically manifest TBE. It enables early confirmation of diagnosis already in the acute phase of the disease and thus it can be instrumental in differential diagnosis and rational therapy, e.g., the administration of specific hyperimmune gamma-globulin.
间接免疫荧光技术,以感染和未感染蜱传脑炎(TBE)病毒的PS细胞悬液作为含抗原底物,提供了一种快速实用的检测方法,能够在临床显性蜱传脑炎的初始阶段检测出特异性IgM类血清抗体。它能在疾病急性期就实现早期诊断确认,因此有助于鉴别诊断和合理治疗,例如给予特异性高效价免疫球蛋白。