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两种口腔消毒方案治疗 2 型糖尿病伴牙周炎患者的效果比较。

Comparative Evaluation of the Effectiveness of and Chlorhexidine in Full-mouth Disinfection Treatment of Periodontitis in Type 2 Diabetes Patients.

机构信息

Department of Periodontics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Wardha, Maharashtra, India, Phone: +91 9834240701, e-mail:

Department of Periodontics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Wardha, Maharashtra, India.

出版信息

J Contemp Dent Pract. 2023 Oct 1;24(10):798-801. doi: 10.5005/jp-journals-10024-3573.

Abstract

AIM

To evaluate and compare the efficacy of and chlorhexidine (CHX) in the treatment of stages II and III periodontitis with one-stage complete mouth disinfection in type 2 diabetes mellitus (DM) patients.

MATERIALS AND METHODS

A total of 24 type 2 diabetic subjects with either stage II or stage III periodontitis were randomly divided into test and control groups with 12 patients in each group. For control group, full-mouth disinfection (FMD) was done using CHX and for test group, FMD was done using . Clinical parameters were evaluated at baseline and at 6 months which comprised of probing pocket depth (PPD), plaque index (PI), clinical attachment level (CAL), papillary bleeding index (PBI). The primary outcomes considered were a reduction in PPD and a gain in CAL. The data were recorded, tabulated, and statistically analyzed.

RESULTS

The PPD reduction for the test group was 3.38 ± 0.75 mm and for the control group was 3.39 ± 0.76 mm. The CAL gain for the test group was 3.39 ± 0.76 mm and for the control group was 3.18 ± 0.74 mm. Although there was a statistically significant PPD reduction, statistically not significant CAL gain was observed.

CONCLUSION

Both the groups with the FMD protocol showed beneficial results in terms of PPD reduction and CAL gain but the test group showed slightly better results.

CLINICAL RELEVANCE

Clinically, there is more PPD reduction and CAL gain from baseline to 6 months in the test group compared to the control group. Clinically, the test group has more favorable results compared to the control group.

摘要

目的

评估和比较 2 型糖尿病患者行一期全口消毒时, 和洗必泰(CHX)在治疗 2 期和 3 期牙周炎方面的疗效。

材料和方法

共 24 名 2 型糖尿病伴 2 期或 3 期牙周炎的患者,随机分为试验组和对照组,每组各 12 名患者。对照组采用 CHX 进行全口消毒(FMD),试验组采用 进行 FMD。基线和 6 个月时评估临床参数,包括探诊牙周袋深度(PPD)、菌斑指数(PI)、临床附着水平(CAL)、乳头出血指数(PBI)。主要结局指标为 PPD 减少和 CAL 增加。记录、制表和统计分析数据。

结果

试验组 PPD 减少 3.38 ± 0.75mm,对照组 PPD 减少 3.39 ± 0.76mm。试验组 CAL 增加 3.39 ± 0.76mm,对照组 CAL 增加 3.18 ± 0.74mm。虽然 PPD 减少有统计学意义,但 CAL 增加无统计学意义。

结论

FMD 方案的两组在 PPD 减少和 CAL 增加方面均显示出有益的结果,但试验组的结果略好。

临床相关性

与对照组相比,试验组在 6 个月时从基线到 6 个月时的 PPD 减少和 CAL 增加更明显。与对照组相比,试验组具有更有利的临床结果。

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