Tso P L, Bringaze W L, Dauterive A H, Correa P, Cohn I
Cancer. 1987 Apr 1;59(7):1362-5. doi: 10.1002/1097-0142(19870401)59:7<1362::aid-cncr2820590722>3.0.co;2-0.
Thirty-eight cases of gastric carcinoma in patients 35-years-old and younger, occurring in the period 1948 to 1983, are reviewed. They comprised 2.2% of 1710 cases in all ages for the same 35 year period at the Charity Hospital. Women were afflicted as commonly as men. Blacks outnumbered whites 2.9:1.0. Obstruction, pain, and weight loss of relatively short duration were prominent symptoms. Tumors tended to be located distally in the stomach, and scirrhous in appearance. Histologically, diffuse type lesions were more common than intestinal or other type tumors. Radiographic evidence of disease was usually present in patients undergoing upper gastrointestinal series. Endoscopy with biopsy was a valuable diagnostic tool. Resectability in this group was not less than that achieved for all ages, however, only one patient has survived for five years. Advanced stage lesions predominated and were associated with poor survival. Earlier stage lesions in this age group appear to bear a more favorable prognosis.
回顾了1948年至1983年期间35岁及以下的38例胃癌患者。在慈善医院同一35年期间的所有年龄段的1710例病例中，它们占2.2%。女性患病情况与男性相同。黑人与白人的比例为2.9:1.0，黑人数量超过白人。梗阻、疼痛和相对较短时间内的体重减轻是突出症状。肿瘤倾向于位于胃的远端，外观为硬癌。组织学上，弥漫型病变比肠型或其他类型肿瘤更常见。接受上消化道造影的患者通常有疾病的影像学证据。内镜检查及活检是一种有价值的诊断工具。该组患者的可切除性不低于所有年龄段患者，但只有1例患者存活了5年。晚期病变占主导，且生存率低。该年龄组的早期病变似乎预后更有利。
