Department of Neurosurgery, Lilavati Hospital and Research Center, Mumbai, India.
Seth G.S. Medical College and K.E.M. Hospital, Mumbai, India.
Acta Neurochir Suppl. 2023;135:265-272. doi: 10.1007/978-3-031-36084-8_41.
This chapter reviews the clinical entity of central or axial atlantoaxial instability (CAAD).
From January 2018 to November 2020, 15 patients were identified as having CAAD, wherein there was no atlantoaxial instability when analyzed by conventional radiological parameters and wherein there was no evidence of neural or dural compression due to the odontoid process. The patients were identified as having atlantoaxial instability on the basis of the alignment of facets on lateral profile imaging and a range of telltale clinical and radiological indicators. The clinical statuses of the patients were recorded both before and after surgical treatment by using the specially designed Goel symptom severity index and visual analog scale (VAS) scores. All patients were treated via atlantoaxial fixation.
There were six men and nine women ranging in age from 18 to 45 years (average: 37 years). The presenting clinical symptoms were relatively subtle and long-standing. Apart from symptoms that are generally related to neural compromise at the craniovertebral junction, a range of nonspecific cranial and spinal symptoms were prominent. The follow-up time after surgery ranged from 6 to 34 months. All patients showed early postoperative and sustained clinical recovery.
The correct diagnosis and appropriate surgical treatment of CAAD can provide an opportunity for quick and lasting clinical recovery.
本章回顾了枢轴或中轴寰枢关节不稳定(CAAD)的临床实体。
从 2018 年 1 月至 2020 年 11 月,确定了 15 例患者存在 CAAD,其中常规影像学参数分析无寰枢关节不稳定,齿状突无神经或硬脑膜压迫证据。根据侧位影像学上关节面的排列和一系列明显的临床和影像学指标,确定这些患者存在寰枢关节不稳定。通过专门设计的 Goel 症状严重程度指数和视觉模拟评分(VAS)记录患者手术前后的临床状况。所有患者均通过寰枢关节固定进行治疗。
患者为 6 男 9 女,年龄 18 至 45 岁(平均 37 岁)。临床表现相对隐匿且持续时间较长。除了与颅颈交界区神经受压相关的一般症状外,还存在一系列非特异性颅颈症状。术后随访时间为 6 至 34 个月。所有患者术后早期及持续临床恢复良好。
正确诊断和适当的手术治疗 CAAD 可以为快速持久的临床康复提供机会。