Movement and Cognition Laboratory, Department of Physical Therapy, University of Haifa Faculty of Social Welfare and Health Sciences, Haifa, Israel.
Movement and Cognition Laboratory, Department of Physical Therapy, University of Haifa Faculty of Social Welfare and Health Sciences, Haifa, Israel
BMJ Case Rep. 2023 Dec 28;16(12):e255285. doi: 10.1136/bcr-2023-255285.
Several authors have reported finding retained primitive reflexes (RPRs) in individuals with autism spectrum disorders (ASD). This case report describes the reduction of RPRs and changes in cognitive function after transcutaneous electrical nerve stimulation (TENS) of muscle. Three individuals were examined in a study at the Institute for Neurology and Neurosurgery in Havana, Cuba. Two child neurologists, not involved in the study, conducted clinical examinations on each participant and diagnosed each with ASD based on DSM-V criteria and the Autism Diagnostic Interview-Revised (an autism evaluation tool). Each child with ASD possessed a triad of impairments in three domains: social interaction, communication, and repetitive behaviour. Individuals were evaluated by quantitative electroencephalographic measures and tested by standardised cognitive function tests before and after 12 weeks of intervention. These interventions were associated with reduced ASD symptoms in the three domains, significant changes in qEEG network connectivity and significantly improved performance on standardised cognitive tests.
多位作者报告称，在自闭症谱系障碍（ASD）患者中发现了保留的原始反射（RPR）。本病例报告描述了经皮神经电刺激（TENS）肌肉后 RPR 的减少和认知功能的变化。古巴哈瓦那神经病学和神经外科学研究所进行了一项研究，对 3 名参与者进行了检查。两名未参与该研究的儿童神经病学家对每位参与者进行了临床检查，并根据 DSM-V 标准和自闭症诊断访谈修订版（自闭症评估工具）对每位参与者进行了 ASD 诊断。每个患有 ASD 的儿童在三个领域都存在三重障碍：社交互动、沟通和重复行为。在干预前和干预后 12 周，通过定量脑电图测量和标准化认知功能测试对个体进行评估。这些干预措施与三个领域的 ASD 症状减少、qEEG 网络连通性的显著变化以及标准化认知测试的表现显著提高有关。
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