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巴西在新冠大流行期间因延迟诊断导致 HIV/AIDS 诊断率降低和艾滋病死亡率增加。

Reduced HIV/AIDS diagnosis rates and increased AIDS mortality due to late diagnosis in Brazil during the COVID-19 pandemic.

机构信息

Health Science Graduate Program, Universidade Federal de Sergipe, Aracaju, SE, Brazil.

Graduate Program in Teaching and Teacher Training, Universidade Federal de Alagoas, Arapiraca, AL, Brazil.

出版信息

Sci Rep. 2023 Dec 27;13(1):23003. doi: 10.1038/s41598-023-50359-y.

Abstract

The COVID-19 pandemic has severely affected global health, leading to the suspension of numerous routine healthcare services and posing challenges in efforts to control other diseases, such as HIV/AIDS. This study aimed to assess the impact of the COVID-19 pandemic on HIV/AIDS diagnoses and mortality rates in Brazil during 2020 and 2021. The percentage change was calculated to determine whether there was an increase or decrease in HIV/AIDS diagnoses and mortality, considering the average numbers from the last 5 years. Additionally, a Joinpoint regression model and an interrupted time series analysis were applied to assess time trends before and after the onset of the pandemic. Lastly, choropleth maps were prepared. We observed a reduction of 22.4% (2020) and 9.8% (2021) in the diagnosis of HIV/AIDS in Brazil. Conversely, there was a significant increase in the percentage change of late diagnosis of AIDS deaths in 2020 (6.9%) and 2021 (13.9%), with some states showing an increase of over 87%. Decreasing time trends in the diagnosis of HIV/AIDS were identified before the pandemic in Brazil, especially in the Southeast and South regions, and then time trends stabilized after including the pandemic years. Along with the dissemination of COVID-19, there was a reduction in the diagnosis of HIV/AIDS and an increase in late diagnosis AIDS deaths, signaling a serious impact of the pandemic on HIV/AIDS control strategies in Brazil. Therefore, we highlight the need for continuous efforts to control both diseases, that is, maintaining regular health services even in crisis situations.

摘要

COVID-19 大流行严重影响了全球健康,导致许多常规医疗服务暂停,并对控制其他疾病(如艾滋病毒/艾滋病)构成挑战。本研究旨在评估 2020 年和 2021 年 COVID-19 大流行对巴西艾滋病毒/艾滋病诊断和死亡率的影响。计算百分比变化,以确定艾滋病毒/艾滋病诊断和死亡率是增加还是减少,考虑到过去 5 年的平均值。此外,还应用了 Joinpoint 回归模型和中断时间序列分析来评估大流行前后的时间趋势。最后,准备了专题地图。我们观察到巴西艾滋病毒/艾滋病诊断减少了 22.4%(2020 年)和 9.8%(2021 年)。相反,2020 年(6.9%)和 2021 年(13.9%)艾滋病晚期诊断死亡百分比变化显著增加,一些州的增幅超过 87%。在巴西,大流行前艾滋病毒/艾滋病的诊断时间趋势呈下降趋势,特别是在东南部和南部地区,然后在包括大流行年份后,时间趋势稳定下来。随着 COVID-19 的传播,艾滋病毒/艾滋病的诊断减少,艾滋病晚期诊断死亡增加,表明大流行对巴西艾滋病毒/艾滋病控制策略产生了严重影响。因此,我们强调需要继续努力控制这两种疾病,即在危机情况下也要维持常规卫生服务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adbe/10754892/084eeca5f9f1/41598_2023_50359_Fig1_HTML.jpg

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