Paul Axler Jean, Louis Rebecca St, Julien Adonai Aly Isaac, Florvil Frednel, Blaise Wendell
General Medicine Department, State University of Haiti, Port-au-Prince, Haiti.
Department of Emergency, University Hospital of Mirebalais, Mirebalais, Haiti.
Arch Clin Cases. 2023 Dec 28;10(4):196-199. doi: 10.22551/2023.41.1004.10274. eCollection 2023.
Bullosis diabeticorum is a rare skin complication of diabetes mellitus, characterized by sudden onset bullous lesions with no history of trauma. It predominantly affects men and has an acral asymmetric presentation. Here, we report a case of bullous disease in a diabetic patient with morbid obesity, the first described in Haiti. A 40-year-old woman, with a strong history of diabetic for five years, poorly controlled and morbidly obese presented to our emergency for bullosis lesions in her limb. She had a prior presentation about two years ago and, approximately a week before this actual presentation, the same symptomatology occurred suddenly without any trauma. After evaluation and screening, the diagnosis of bullosis diabeticorum was kept. She was initially treated with antibiotics due to signs of superinfection. However, as soon as the symptoms improved, antibiotics were discontinued. An antiseptic lotion and topical antibiotic, neomycin, were used along with daily dressings. About a week after, her blood glucose came to control, signs of infection disappeared as did the bullous lesions and surgical evaluation was performed to ensure proper wound evolution. She was educated by a nutritionist, and our team emphasized the importance of regular follow-up at the hospital. Diabetic bullous disease is very rare and easy to confuse with other diabetic skin complications. A good clinical history is essential to make the diagnosis, and management requires good therapeutic education to avoid the burdensome complications of diabetes.
糖尿病大疱病是糖尿病一种罕见的皮肤并发症,其特征为突然出现无创伤史的大疱性皮损。该病主要累及男性,呈肢端不对称性表现。在此,我们报告一例海地首例患严重肥胖症的糖尿病患者发生大疱病的病例。一名40岁女性,有5年糖尿病史,病情控制不佳且患有严重肥胖症,因肢体出现大疱病皮损前来我院急诊。她大约两年前曾有过一次发病,在此次实际就诊前约一周,同样的症状突然出现且无任何创伤。经过评估和筛查,确诊为糖尿病大疱病。由于存在超级感染迹象,她最初接受了抗生素治疗。然而,症状一改善,抗生素就停用了。使用了一种消毒洗剂和外用抗生素新霉素,并每日换药。大约一周后,她的血糖得到控制,感染迹象消失,大疱性皮损也消失了,并进行了手术评估以确保伤口正常愈合。一名营养师对她进行了指导,我们的团队强调了在医院定期随访的重要性。糖尿病大疱病非常罕见,容易与其他糖尿病皮肤并发症相混淆。良好的临床病史对于做出诊断至关重要,治疗需要良好的治疗指导以避免糖尿病带来的沉重并发症负担。