QuitSure智能手机应用程序用于戒烟的有效性：一项前瞻性单臂试验的结果

Effectiveness of the QuitSure Smartphone App for Smoking Cessation: Findings of a Prospective Single Arm Trial.

作者信息

Pandya Apurvakumar, K S Mythri, Mishra Shweta, Bajaj Kriti

机构信息

Parul Institute of Public Health, Parul University, Vadodara, India.

Indian Institute of Public Health, Gandhinagar, India.

出版信息

JMIR Form Res. 2023 Dec 29;7:e51658. doi: 10.2196/51658.

DOI:10.2196/51658

PMID:38157243

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10787327/

Abstract

BACKGROUND

Digital therapies, especially smartphone apps for active and continuous smoking cessation support, are strongly emerging as an alternative smoking cessation therapy. In the Indian context, there is a growing interest in the use of app-based smoking cessation programs; however, there is limited evidence regarding their effectiveness in achieving long-term continuous abstinence.

OBJECTIVE

This study aimed to evaluate the long-term abstinence effect (up to 30-d abstinence postprogram completion) of a smartphone app, QuitSure, for smoking cessation in active smokers from India.

METHODS

In this prospective single-arm study, participants who signed up for the QuitSure app were enrolled in this study. The primary end point was the prolonged abstinence (PA) rate from weeks 1 to 4 (day 7 to day 30). Furthermore, data for withdrawal symptoms, relapse reasons, and reasons for not continuing the program were also assessed.

RESULTS

The quit rate was calculated considering only the participants who followed up and completed the survey sent to them (per protocol) at day 7 and at day 30, respectively. The PA rate at day 7 was found to be 64.5% (111/172; 95% CI 56% to 72%), and the PA rate at day 30 was found to be 55.8% (72/129; 95% CI 45% to 65%). Within the 7-day abstinence period, 60.4% (67/111) of the participants did not have any withdrawal symptoms. The most common mild withdrawal symptoms were mild sleep disturbance (21/111, 18.9%), mild digestive changes (19/111, 17.1%), and coughing (17/111, 15.3%). Severe withdrawal symptoms were rare, with only 5.4% (6/111) experiencing them. For those achieving 30-day postprogram abstinence, 85% (61/72) had no mild withdrawal symptoms, and 99% (71/72) had no severe withdrawal symptoms. Among successful quitters at day 7, a total of 72.1% (80/111) reported minimal to no cravings, which increased to 88% (63/72) at day 30. Furthermore, 78% (56/72) of those with PA at day 30 reported no change in weight or reduced weight. Among participants experiencing relapse, 48% (28/58) cited intense cravings, 28% (16/58) mentioned facing a tragedy, and 26% (15/58) reported relapsing due to alcohol consumption. The PA rates as a result of the QuitSure program were found to be better than those reported in the results of other smoking-cessation app programs' studies.

CONCLUSIONS

The QuitSure app yields high PA rates and ameliorates symptoms associated with smoking cessation. In order to obtain conclusive evidence regarding the effectiveness and efficacy of the QuitSure program, future research should include appropriate control measures. Nevertheless, the QuitSure program can serve as a valuable adjunct to a conventional smoking cessation treatment program to aid sustained abstinence.

摘要

背景

数字疗法，尤其是用于积极和持续戒烟支持的智能手机应用程序，正迅速成为一种替代戒烟疗法。在印度，人们对基于应用程序的戒烟项目的兴趣日益浓厚；然而，关于其在实现长期持续戒烟方面的有效性的证据有限。

目的

本研究旨在评估一款智能手机应用程序QuitSure对印度现役吸烟者戒烟的长期戒断效果（项目完成后长达30天的戒断）。

方法

在这项前瞻性单臂研究中，报名参加QuitSure应用程序的参与者被纳入本研究。主要终点是第1至4周（第7天至第30天）的延长戒断（PA）率。此外，还评估了戒断症状、复发原因以及未继续该项目的原因的数据。

结果

仅考虑分别在第7天和第30天跟进并完成发送给他们的调查（按方案）的参与者来计算戒烟率。第7天的PA率为64.5%（111/172；95%CI 56%至72%），第30天的PA率为55.8%（72/129；95%CI 45%至65%）。在7天的戒断期内，60.4%（67/111）的参与者没有任何戒断症状。最常见的轻度戒断症状是轻度睡眠障碍（21/111，18.9%）、轻度消化变化（19/111，17.1%）和咳嗽（17/111，15.3%）。严重戒断症状很少见，只有5.4%（6/111）的人经历过。对于那些在项目后实现30天戒断的人，85%（61/72）没有轻度戒断症状，99%（71/72）没有严重戒断症状。在第7天成功戒烟者中，共有72.1%（80/111）报告极少或没有渴望，到第30天这一比例增至88%（63/72）。此外，第30天有PA的人中，78%（56/72）报告体重没有变化或体重减轻。在经历复发的参与者中，48%（28/58）提到强烈渴望，28%（16/58）提到遭遇悲剧，26%（15/58）报告因饮酒而复吸。发现QuitSure项目导致的PA率优于其他戒烟应用程序项目研究结果中报告的PA率。