Shulkin B L, Shapiro B, Francis I R, Dorr R, Shen S W, Sisson J C
Clin Nucl Med. 1986 Dec;11(12):851-4. doi: 10.1097/00003072-198612000-00012.
I-131 metaiodobenzylguanidine (I-131 MIBG) is a well established imaging agent that reliably detects pheochromocytoma. In some patients, however, I-131 MIBG may fail to localize pheochromocytoma. I-123 MIBG has several potential advantages over I-131 MIBG, and these advantages may enable locating pheochromocytomas which have eluded other techniques, including I-131 MIBG imaging. A patient with primary extra-adrenal pheochromocytoma is described who illustrates the superiority of I-123 MIBG for the imaging of pheochromocytoma.
碘-131间碘苄胍(I-131 MIBG)是一种成熟的成像剂,能可靠地检测嗜铬细胞瘤。然而,在一些患者中,I-131 MIBG可能无法定位嗜铬细胞瘤。与I-131 MIBG相比,碘-123 MIBG有几个潜在优势,这些优势可能使定位那些其他技术(包括I-131 MIBG成像)未能发现的嗜铬细胞瘤成为可能。本文描述了一名原发性肾上腺外嗜铬细胞瘤患者,该病例说明了碘-123 MIBG在嗜铬细胞瘤成像方面的优越性。