Pandita Shivali, Singh Sanchita, Bajpai Sanjay Kumar, Mishra Geetanjali, Saxena Gauri, Verma Praveen C
CSIR-National Botanical Research Institute, (Council of Scientific and Industrial Research) Rana Pratap Marg, Lucknow, UP, 226001, India; Department of Zoology, University of Lucknow, Lucknow, Uttar Pradesh, 226007, India.
CSIR-National Botanical Research Institute, (Council of Scientific and Industrial Research) Rana Pratap Marg, Lucknow, UP, 226001, India; Department of Botany, University of Lucknow, Lucknow, Uttar Pradesh, 226007, India.
Dev Biol. 2024 Mar;507:64-72. doi: 10.1016/j.ydbio.2023.12.011. Epub 2023 Dec 30.
Regeneration is a fascinating phenomenon observed in various organisms across the animal kingdom. Different orders of class Insecta are reported to possess comprehensive regeneration abilities. Several signalling molecules, such as morphogens, growth factors, and others trigger a cascade of events that promote wound healing, blastema formation, growth, and repatterning. Furthermore, epigenetic regulation has emerged as a critical player in regulating the process of regeneration. This report highlights the major breakthrough research on wound healing and tissue regeneration. Exploring and reviewing the molecular basis of regeneration can be helpful in the area of regenerative medicine advancements. The understanding gathered from this framework can potentially contribute to hypothesis designing with implications in the field of synthetic biology and human health.
再生是动物界各种生物体中观察到的一种迷人现象。据报道，昆虫纲的不同目具有全面的再生能力。几种信号分子，如形态发生素、生长因子等，引发一系列促进伤口愈合、芽基形成、生长和重新模式化的事件。此外，表观遗传调控已成为调节再生过程的关键因素。本报告重点介绍了伤口愈合和组织再生方面的重大突破性研究。探索和回顾再生的分子基础有助于再生医学的发展。从这个框架中获得的认识可能有助于在合成生物学和人类健康领域进行假设设计。
