A pulse generating and data recording system based on the microcomputer PDP 11/23.

A widely applicable measuring system, especially suited for all types of 'voltage-clamp' (including 'patch-clamp') experiments, is presented. It is mainly based on commercially available hardware and software components. All interfacing with the analog world takes place on the front panel of the microcomputer box. Synchronization of pulse generation with data acquisition and other control actions take advantage of the four upper bits not used by the digital-to-analog converter during direct memory access transfer.