Fournier Jeffrey E, Russell Crispin, Hossain Mohammad
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, CAN.
Division of Thoracic Surgery, Saint John Regional Hospital, Saint John, CAN.
Cureus. 2023 Nov 30;15(11):e49711. doi: 10.7759/cureus.49711. eCollection 2023 Nov.
Endocrine mucin-producing sweat gland carcinoma (EMPSGC) is a rare, low-grade neuroendocrine neoplasm previously believed to be indolent in nature. There have only previously been six reported cases of metastases and none of thoracic structures. This case shows a metastatic EMPSGC in a 72-year-old male with a complex oncologic history and is the first reported case of metastases to the lung. As increased recognition of this entity continues to grow, it is important to consider it as part of the differential in mucinous and/or neuroendocrine neoplasms for appropriate management. This case adds to the oncologic literature by demonstrating a rare cutaneous neoplasm and emphasizing its metastatic potential.
内分泌黏液生成性汗腺癌(EMPSGC)是一种罕见的低级别神经内分泌肿瘤,此前认为其本质上生长缓慢。此前仅有6例关于转移的报道,且均未转移至胸部结构。该病例显示一名72岁男性患有转移性EMPSGC,其有复杂的肿瘤病史,这是首例报道的转移至肺部的病例。随着对该实体的认识不断增加,在对黏液性和/或神经内分泌肿瘤进行适当管理时,将其作为鉴别诊断的一部分加以考虑很重要。该病例通过展示一种罕见的皮肤肿瘤并强调其转移潜能,丰富了肿瘤学文献。