Tsai Jia-Huei, Hsiao Tzu-Lin, Chen Yi-Ying, Hsiao Cheng-Hsiang, Liau Jau-Yu
Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan; Graduate Institute of Pathology, College of Medicine, National Taiwan University, Taipei, Taiwan.
J Cutan Pathol. 2014 Jun;41(6):544-7. doi: 10.1111/cup.12314. Epub 2014 Mar 7.
Cutaneous endocrine mucin-producing sweat gland carcinoma (EMPSGC) is a very rare low-grade malignant neoplasm analogous to the mammary solid-papillary carcinoma. It frequently expresses neuroendocrine markers and may show mucinous differentiation. Although the nodules are circumscribed, myoepithelial cells cannot be showed in most cases and about half of the cases are associated with invasive mucinous carcinoma. Hence, it has been suggested to be invasive and the precursor lesion of some primary cutaneous mucinous carcinomas. After being recognized as a distinct entity, all cases reported to date occurred either in the periocular region or on the cheek. Two thirds of the patients were female. Herein we present an unusual case of in situ EMPSGC on the chest wall skin of a middle-aged man.
皮肤内分泌性黏液生成汗腺癌（EMPSGC）是一种非常罕见的低级别恶性肿瘤，类似于乳腺实性乳头状癌。它常表达神经内分泌标志物，可能表现为黏液样分化。尽管结节边界清晰，但大多数病例中无法显示肌上皮细胞，约一半病例与浸润性黏液癌相关。因此，有人认为它具有侵袭性，是一些原发性皮肤黏液癌的前驱病变。自被确认为一种独特的实体后，迄今为止报道的所有病例均发生在眼周区域或脸颊。三分之二的患者为女性。在此，我们报告一例发生在一名中年男性胸壁皮肤的原位EMPSGC罕见病例。
