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养狗与 2 型糖尿病患者的血糖控制和全因死亡:一项全国性队列研究。

Dog ownership, glycaemic control and all-cause death in patients with newly diagnosed type 2 diabetes: a national cohort study.

机构信息

Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.

The George Institute for Global Health, University of New South Wales, Sydney, NSW, Australia.

出版信息

Front Public Health. 2023 Dec 15;11:1265645. doi: 10.3389/fpubh.2023.1265645. eCollection 2023.

Abstract

AIMS

To evaluate whether dog ownership from the time of type 2 diabetes diagnosis improved glycaemic control, increased achievement of major guideline treatment goals or reduced the risk of all-cause death.

METHODS

Patients diagnosed with type 2 diabetes were followed by linkage of four Swedish national registers covering diabetes, dog ownership, socioeconomics, and mortality. Linear regression was used to estimate the mean yearly change in glycated haemoglobin (HbA1c). Cox survival analysis and logistic regression were used to analyse associations between dog ownership and all-cause death and achievement of treatment goals, respectively.

RESULTS

Of 218,345 individuals included, 8,352 (3.8%) were dog-owners. Median follow-up was 5.2 years. Dog-owners had worse yearly change in HbA1c, and were less likely to reach HbA1c, low-density lipoprotein (LDL), and systolic blood pressure (SBP) treatment goals than non-dog-owners (adjusted odds ratios [95% CI] of 0.93 [0.88-0.97], 0.91 [0.86-0.95], and 0.95 [0.90-1.00], respectively). There was no difference in the risk of all-cause death (adjusted hazard ratio [95% CI] 0.92 [0.81-1.04], dog owners versus not).

CONCLUSION

Owning a dog when diagnosed with diabetes did not lead to better achievement of treatment goals or reduced mortality, but was in fact associated with a smaller reduction in HbA1c and reduced likelihood of achieving treatment goals.

摘要

目的

评估 2 型糖尿病诊断后养狗是否能改善血糖控制,提高主要指南治疗目标的达标率,或降低全因死亡率。

方法

通过链接涵盖糖尿病、狗的拥有情况、社会经济状况和死亡率的四个瑞典国家登记处,对被诊断患有 2 型糖尿病的患者进行随访。采用线性回归来估计糖化血红蛋白(HbA1c)的年平均变化。采用 Cox 生存分析和逻辑回归分别分析狗的拥有情况与全因死亡和治疗目标达标之间的关系。

结果

在纳入的 218345 名患者中,有 8352 人(3.8%)是狗主人。中位随访时间为 5.2 年。与非狗主人相比,狗主人的 HbA1c 年变化更差,达到 HbA1c、低密度脂蛋白(LDL)和收缩压(SBP)治疗目标的可能性更低(调整后的比值比[95%CI]分别为 0.93[0.88-0.97]、0.91[0.86-0.95]和 0.95[0.90-1.00])。全因死亡率无差异(调整后的危险比[95%CI]为 0.92[0.81-1.04],狗主人与非狗主人相比)。

结论

在诊断患有糖尿病时养狗并没有导致更好地实现治疗目标或降低死亡率,但实际上与 HbA1c 降低幅度较小和实现治疗目标的可能性降低有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3cf/10757647/35d3f5eac883/fpubh-11-1265645-g001.jpg

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