Berger Geraint, French Daniel
Dalhousie University Medical School, Halifax, NS B3H 4R2, Canada.
Department of Surgery, Division of Thoracic Surgery, Dalhousie University, VG Site Victoria Building, 1276 South Park Street, Halifax, NS B3H 2Y9, Canada.
J Surg Case Rep. 2023 Dec 30;2023(12):rjad590. doi: 10.1093/jscr/rjad590. eCollection 2023 Dec.
A 71-year-old female presented with progressive dysphagia and unexplained weight loss. Computed tomography and esophagogastroduodenoscopy (EGD) revealed invasive esophageal squamous cell carcinoma, which was initially treated with local radiation and esophageal stenting. Over the next year, the patient experienced multiple symptoms and hospital admissions consistent with a malignant tracheoesophageal fistula, despite negative findings on imaging, bronchoscopy, and EGD. Prophylactic antibiotics were initiated based on symptomatology to prevent septic episodes. Stent erosion into the membranous trachea was eventually observed. Neodymium-yttrium-aluminum-garnet laser bronchoscopy was used periodically to debulk the invading tumor around the stent. A percutaneous endoscopic gastrostomy tube was also inserted to facilitate enteral nutrition and avoid aspiration pneumonia. The patient reported significant improvements in respiratory symptoms following each laser debridement and has progressed well beyond the life expectancy associated with malignant tracheoesophageal fistula.
一名71岁女性因进行性吞咽困难和不明原因体重减轻就诊。计算机断层扫描和食管胃十二指肠镜检查(EGD)显示为浸润性食管鳞状细胞癌,最初接受了局部放疗和食管支架置入治疗。在接下来的一年里,尽管影像学、支气管镜检查和EGD检查结果均为阴性,但患者仍出现了多种与恶性气管食管瘘相符的症状并多次住院。根据症状开始使用预防性抗生素以预防脓毒症发作。最终观察到支架侵蚀进入膜性气管。定期使用钕钇铝石榴石激光支气管镜清除支架周围的侵袭性肿瘤。还插入了经皮内镜下胃造瘘管以促进肠内营养并避免吸入性肺炎。患者报告每次激光清创后呼吸症状有显著改善,并且病情进展良好,远超与恶性气管食管瘘相关的预期寿命。