Koh Matthew Chung Yi, Ngiam Jinghao Nicholas, Yong Joy, Tambyah Paul Anantharajah, Archuleta Sophia
Division of Infectious Diseases, Department of Medicine, National University Hospital, National University Health System, Singapore, Singapore.
Department of Pharmacy, National University Health System, Singapore, Singapore.
HIV Med. 2024 Apr;25(4):504-508. doi: 10.1111/hiv.13604. Epub 2024 Jan 2.
People living with HIV may find personalized access to accurate information on antiretroviral therapy (ART) challenging given the stigma and costs potentially associated with attending physical consultations. Artificial intelligence (AI) chatbots such as ChatGPT may help to lower barriers to accessing information addressing concerns around ART initiation. However, the safety and accuracy of the information provided remains to be studied.
We instructed ChatGPT to answer questions that people living with HIV frequently ask about ART, covering i) knowledge of and access to ART; ii) ART initiation, side effects, and adherence, and iii) general sexual health practices while receiving ART. We checked the accuracy of the advice against international HIV clinical practice guidelines.
ChatGPT answered all questions accurately and comprehensively. It recognized potentially life-threatening scenarios such as abacavir hypersensitivity reaction and gave appropriate advice. However, in certain contexts, such as specific geographic locations or for pregnant individuals, the advice lacked specificity to an individual's unique circumstances and may be inadequate. Nevertheless, ChatGPT consistently re-directed the individual to seek help from a healthcare professional to obtain targeted advice.
ChatGPT may act as a useful adjunct in the process of ART counselling for people living with HIV. Improving access to information on and knowledge about ART may improve access and adherence to ART and outcomes for people living with HIV overall.
鉴于参加面对面咨询可能存在的耻辱感和成本,感染艾滋病毒的人可能会发现个性化获取抗逆转录病毒疗法(ART)的准确信息具有挑战性。诸如ChatGPT之类的人工智能(AI)聊天机器人可能有助于降低获取信息的障碍,解决围绕开始抗逆转录病毒治疗的担忧。然而,所提供信息的安全性和准确性仍有待研究。
我们指示ChatGPT回答感染艾滋病毒的人经常问到的关于抗逆转录病毒治疗的问题,涵盖:i)对抗逆转录病毒治疗的了解和获取;ii)开始抗逆转录病毒治疗、副作用和依从性,以及iii)接受抗逆转录病毒治疗期间的一般性健康性行为。我们对照国际艾滋病毒临床实践指南检查了建议的准确性。
ChatGPT准确、全面地回答了所有问题。它识别出了潜在的危及生命的情况,如阿巴卡韦超敏反应,并给出了适当的建议。然而,在某些情况下,如特定地理位置或孕妇的情况,建议缺乏针对个人独特情况的特异性,可能不够充分。尽管如此,ChatGPT始终引导个人向医疗保健专业人员寻求帮助以获得有针对性的建议。
ChatGPT可能在为感染艾滋病毒的人提供抗逆转录病毒治疗咨询的过程中起到有用的辅助作用。改善获取抗逆转录病毒治疗信息和知识的机会可能会改善感染艾滋病毒的人的治疗获取、依从性及总体治疗效果。