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本文引用的文献

1
Blockade of Proteinase-Activated Receptor 2 (PAR2) Attenuates Neuroinflammation in Experimental Autoimmune Encephalomyelitis.蛋白酶激活受体 2（PAR2）阻断减轻实验性自身免疫性脑脊髓炎的神经炎症。
J Pharmacol Exp Ther. 2024 Jan 2;388(1):12-22. doi: 10.1124/jpet.123.001685.
2
Current Updates on the Diagnosis and Management of Multiple Sclerosis for the General Neurologist.普通神经科医生对多发性硬化症诊断与治疗的最新进展
J Clin Neurol. 2023 May;19(3):217-229. doi: 10.3988/jcn.2022.0208.
3
Allosteric Regulation of G-Protein-Coupled Receptors: From Diversity of Molecular Mechanisms to Multiple Allosteric Sites and Their Ligands.别构调节 G 蛋白偶联受体：从分子机制多样性到多个别构结合位点及其配体。
Int J Mol Sci. 2023 Mar 24;24(7):6187. doi: 10.3390/ijms24076187.
4
Conventional and pathogenic Th2 cells in inflammation, tissue repair, and fibrosis.炎症、组织修复和纤维化中的传统和致病 Th2 细胞。
Front Immunol. 2022 Aug 9;13:945063. doi: 10.3389/fimmu.2022.945063. eCollection 2022.
5
Protease-activated receptors in health and disease.蛋白酶激活受体在健康和疾病中的作用。
Physiol Rev. 2023 Jan 1;103(1):717-785. doi: 10.1152/physrev.00044.2021. Epub 2022 Jul 28.
6
The activation fragment of PAR2 is elevated in serum from patients with rheumatoid arthritis and reduced in response to anti-IL6R treatment.PAR2 的激活片段在类风湿关节炎患者的血清中升高，并对抗 IL-6R 治疗有反应降低。
Sci Rep. 2021 Dec 20;11(1):24285. doi: 10.1038/s41598-021-03346-0.
7
Protease-activated receptor 2 stabilizes Bcl-xL and regulates EGFR-targeted therapy response in colorectal cancer.蛋白酶激活受体 2 稳定 Bcl-xL 并调节结直肠癌中表皮生长因子受体靶向治疗的反应。
Cancer Lett. 2021 Oct 1;517:14-23. doi: 10.1016/j.canlet.2021.05.040. Epub 2021 Jun 10.
8
Ensheathment and Myelination of Axons: Evolution of Glial Functions.轴突的鞘形成和髓鞘化：神经胶质功能的演化。
Annu Rev Neurosci. 2021 Jul 8;44:197-219. doi: 10.1146/annurev-neuro-100120-122621. Epub 2021 Mar 15.
9
Mechanisms underlying progression in multiple sclerosis.多发性硬化症进展的机制。
Curr Opin Neurol. 2020 Jun;33(3):277-285. doi: 10.1097/WCO.0000000000000818.
10
Plasma kallikrein modulates immune cell trafficking during neuroinflammation via PAR2 and bradykinin release.血浆激肽释放酶通过 PAR2 和缓激肽释放来调节神经炎症中的免疫细胞迁移。
Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):271-276. doi: 10.1073/pnas.1810020116. Epub 2018 Dec 17.

PARting Neuroinflammation with Protease-Activated Receptor 2 Pepducins.

作者信息

Scarisbrick Isobel A

机构信息

Center for Regenerative Biotherapeutics, Department of Physical Medicine and Rehabilitation, and Department of Physiology and Biomedical Engineering, Mayo Clinic Graduate School of Biomedical Sciences, Regenerative Sciences, Rochester, Minnesota

出版信息

J Pharmacol Exp Ther. 2024 Jan 2;388(1):8-11. doi: 10.1124/jpet.123.001893.

DOI:10.1124/jpet.123.001893
PMID:38169447
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12164717/
Abstract
摘要