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[向大鼠下丘脑和脑第三脑室注射神经降压素后胃嗜银细胞的功能变化及大鼠脑电活动]

[Functional changes in the argentaffin cells of the stomach and electrical activity of the brain of the rat after injection of neurotensin into the hypothalamus and 3d ventricle of the brain].

作者信息

Kotel'nikova V I, Chernysheva M P, Mileĭkovskiĭ B Iu

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1986 Dec;72(12):1665-72.

PMID:3817211
Abstract

Administration of neurotensin or its analogue into the hypothalamic structures altered the degree of activity synchronization among hypothalamic and brain-stem structures, the synchronization becoming most obvious among ventro-medial nucleus, amygdala and the central grey matter. Administration of the drugs into the 3rd ventricle and paraventricular nuclei suggested antagonistic effects of these peptides at the hypothalamic level. The data obtained could be regarded as local effects of the neuropeptides upon neurons of the paraventricular nucleus and as systemic effects upon argentaffin cells of the stomach antral portion.

摘要

将神经降压素或其类似物注入下丘脑结构会改变下丘脑和脑干结构之间的活动同步程度,这种同步在腹内侧核、杏仁核和中央灰质之间最为明显。将这些药物注入第三脑室和室旁核表明这些肽在下丘脑水平具有拮抗作用。所获得的数据可被视为神经肽对室旁核神经元的局部作用以及对胃窦部嗜银细胞的全身作用。

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