Department of Radiology, Ege University Faculty of Medicine, 35100, Bornova, Izmir State, Turkey.
Sci Rep. 2024 Jan 3;14(1):447. doi: 10.1038/s41598-023-50798-7.
Suspicious architectural distortion is an elusive finding in breast cancer diagnosis. This study aimed to evaluate the diagnostic accuracy of the Kaiser score for suspicious architectural distortions observed on mammography and compare it with the BI-RADS score of the lesion. Mammograms performed between January 2013 and March 2023 were retrospectively analyzed for the presence of suspicious architectural distortion. Forty-one patients, who had at least 1 year of radiological follow-up or pathology results, and underwent breast MRI, were included in the study. Mammography findings and the BI-RADS category of the lesion were assessed. MRI findings were evaluated and Kaiser scoring was performed according to the tree flowchart. Ninety-one percent of the enhanced lesions had a Kaiser score of 5 and above. In the diagnosis of malignancy, the Kaiser score yielded an accuracy of 75.61% (AUC 0.833). A statistically significant correlation was observed indicating that a malignant diagnosis was more prevalent in patients with a Kaiser score of 5 and above (p < 0.05). Additionally statistically significant relationship was also observed between the BI-RADS category of architectural distortions on mammography and the Kaiser score (p = 0.007). The combined utilization of mammography findings and the evidence-based Kaiser score in suspected architectural distortions provides more accurate results in the differential diagnosis of breast cancer.
可疑的结构扭曲是乳腺癌诊断中难以捉摸的发现。本研究旨在评估 Kaiser 评分在乳腺摄影中可疑结构扭曲的诊断准确性,并将其与病变的 BI-RADS 评分进行比较。回顾性分析了 2013 年 1 月至 2023 年 3 月期间进行的乳腺 X 线摄影,以确定是否存在可疑的结构扭曲。本研究纳入了 41 例至少有 1 年影像学随访或病理结果且接受过乳腺 MRI 的患者。评估了乳腺 X 线摄影结果和病变的 BI-RADS 类别。对 MRI 结果进行评估,并根据树形流程图进行 Kaiser 评分。91%的增强病变的 Kaiser 评分为 5 分及以上。在恶性肿瘤的诊断中,Kaiser 评分的准确率为 75.61%(AUC 0.833)。观察到统计学上的显著相关性,表明 Kaiser 评分 5 分及以上的患者更易发生恶性诊断(p<0.05)。此外,在乳腺摄影上结构扭曲的 BI-RADS 类别与 Kaiser 评分之间也观察到统计学显著关系(p=0.007)。在可疑结构扭曲的情况下,结合使用乳腺 X 线摄影结果和基于证据的 Kaiser 评分可以提供更准确的乳腺癌鉴别诊断结果。