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凯泽评分在评估乳腺癌患者分期MRI检查中发现的额外乳腺病变时的可靠性

Reliability of Kaiser Score in Assessing Additional Breast Lesions Identified on Staging MRI in Patients with Breast Cancer.

作者信息

Hijazi Madiha, Chahine Reve, Berjawi Ghina, Jabbour Yara, El Annan Tamara, Ibrahim Roy, Nassar Lara

机构信息

Department of Diagnostic Radiology, American University of Beirut Medical Center, Beirut 1107, Lebanon.

Department of Diagnostic Radiology, Lebanese American University Medical Center, Beirut 1100, Lebanon.

出版信息

Diagnostics (Basel). 2024 Aug 8;14(16):1726. doi: 10.3390/diagnostics14161726.

DOI:10.3390/diagnostics14161726
PMID:39202214
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11353333/
Abstract

(1) Background: The Kaiser score is a user-friendly tool that evaluates lesions on breast MRI and has been studied in the general population and a few specific clinical scenarios. We aim to evaluate the performance of the Kaiser score in the characterization of additional lesions identified on staging breast MRI. (2) Methods: The Kaiser score of the biopsied additional lesions identified on staging MRI in recently diagnosed breast cancer patients was retrospectively determined. Statistical analysis was performed to evaluate the diagnostic capability of the Kaiser score and whether it is affected by different imaging and pathological parameters of the additional and the index lesion. (3) Results: Seventy-six patients with ninety-two MRI-detected lesions constitute the studied population. There was a statistically significant difference in the Kaiser score between benign and malignant lesions, irrespective of the pathology of the index cancer ( = 0.221) or the size and the imaging features of the additional lesion. Using a cutoff of 5 and above for suspicious lesions, biopsy could have been avoided in 34/92 lesions. (4) Conclusions: The Kaiser score can assist radiologists in the evaluation of additional MRI lesions identified in recently diagnosed breast cancer patients, thus decreasing the number of unneeded biopsies and delays in definitive surgical management.

摘要

(1) 背景:凯泽评分是一种便于使用的工具,用于评估乳腺MRI上的病变,已在普通人群和一些特定临床场景中进行了研究。我们旨在评估凯泽评分在对分期乳腺MRI上发现的额外病变进行特征描述方面的性能。(2) 方法:回顾性确定近期诊断为乳腺癌患者分期MRI上活检的额外病变的凯泽评分。进行统计分析以评估凯泽评分的诊断能力,以及它是否受额外病变和索引病变的不同影像及病理参数影响。(3) 结果:76例患者的92个MRI检测到的病变构成了研究人群。无论索引癌的病理情况(P = 0.221)或额外病变的大小及影像特征如何,良性和恶性病变之间的凯泽评分存在统计学显著差异。将可疑病变的临界值设定为5及以上,92个病变中的34个可避免活检。(4) 结论:凯泽评分可协助放射科医生评估近期诊断为乳腺癌患者MRI上发现的额外病变,从而减少不必要的活检数量以及确定性手术治疗的延迟。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b73/11353333/7c6ffba16d2f/diagnostics-14-01726-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b73/11353333/bc9600a60d36/diagnostics-14-01726-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b73/11353333/9daa0e229107/diagnostics-14-01726-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b73/11353333/23c118a1edd2/diagnostics-14-01726-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b73/11353333/e371a51788d2/diagnostics-14-01726-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b73/11353333/b94f1d1a74fe/diagnostics-14-01726-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b73/11353333/7c6ffba16d2f/diagnostics-14-01726-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b73/11353333/bc9600a60d36/diagnostics-14-01726-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b73/11353333/9daa0e229107/diagnostics-14-01726-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b73/11353333/23c118a1edd2/diagnostics-14-01726-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b73/11353333/e371a51788d2/diagnostics-14-01726-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b73/11353333/b94f1d1a74fe/diagnostics-14-01726-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b73/11353333/7c6ffba16d2f/diagnostics-14-01726-g006.jpg

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本文引用的文献

1
Enhancing the Kaiser score for lesion characterization in unenhanced breast MRI.增强 Kaiser 评分以对未增强乳腺 MRI 中的病灶特征进行分析。
Eur J Radiol. 2024 Jul;176:111520. doi: 10.1016/j.ejrad.2024.111520. Epub 2024 May 20.
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Radiologic-Pathologic Correlation of Nonmass Enhancement Contiguous with Malignant Index Breast Cancer Masses at Preoperative Breast MRI.术前乳腺 MRI 中与恶性指数乳腺癌肿块相邻的非肿块样增强的放射-病理相关性。
Radiol Imaging Cancer. 2024 Mar;6(2):e230060. doi: 10.1148/rycan.230060.
3
It's Complicated: Managing Nonmass Enhancement Found at Breast MRI in Patients with Newly Diagnosed Cancer.
情况复杂:新诊断癌症患者乳腺MRI检查发现非肿块强化的处理
Radiol Imaging Cancer. 2024 Mar;6(2):e240003. doi: 10.1148/rycan.240003.
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Using the Kaiser Score as a clinical decision rule for breast lesion classification: Does computer-assisted curve type analysis improve diagnosis?使用 Kaiser 评分作为乳腺病变分类的临床决策规则:计算机辅助曲线类型分析是否能提高诊断准确率?
Eur J Radiol. 2024 Jan;170:111271. doi: 10.1016/j.ejrad.2023.111271. Epub 2023 Dec 19.
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Diagnostic accuracy of the breast MRI Kaiser score in suspected architectural distortions and its comparison with mammography.乳腺 MRI Kaiser 评分对疑似结构扭曲的诊断准确性及其与乳腺 X 线摄影的比较。
Sci Rep. 2024 Jan 3;14(1):447. doi: 10.1038/s41598-023-50798-7.
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Added value of clinical decision rules for the management of enhancing breast MRI lesions: A systematic comparison of the Kaiser score and the Göttingen score.临床决策规则在增强型乳腺 MRI 病变管理中的附加价值:凯撒评分与哥廷根评分的系统比较。
Eur J Radiol. 2023 Dec;169:111185. doi: 10.1016/j.ejrad.2023.111185. Epub 2023 Nov 4.
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Additional occult cancers identified on staging breast MRI: imaging appearances and pathologic characteristics. 分期乳腺 MRI 检查中发现的其他隐匿性癌症:影像学表现和病理特征。
J Med Radiat Sci. 2023 Dec;70(4):360-368. doi: 10.1002/jmrs.694. Epub 2023 Jun 20.
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[Breast Imaging Reporting and Data System (BI-RADS): Advantages and Limitations].[乳腺影像报告和数据系统(BI-RADS):优势与局限性]
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Effects of preoperative magnetic resonance image on survival rates and surgical planning in breast cancer conservative surgery: randomized controlled trial (BREAST-MRI trial).术前磁共振成像对乳腺癌保乳手术生存率和手术计划的影响:随机对照试验(BREAST-MRI 试验)。
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BI-RADS 3 Assessment on MRI: A Lesion-Based Review for Breast Radiologists.MRI上的BI-RADS 3评估:针对乳腺放射科医生的基于病变的综述
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