Department of Pharmaceutics, Netaji Subhas Chandra Bose Institute of Pharmacy, Chakdaha, Nadia - 741222, West Bengal, India.
Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, 751003, Odisha, India.
Curr Drug Deliv. 2024;21(11):1445-1459. doi: 10.2174/0115672018286832231218112557.
Bioelectronic medicine is a multidisciplinary field that combines molecular medicine, neurology, engineering, and computer science to design devices for diagnosing and treating diseases. The advancements in bioelectronic medicine can improve the precision and personalization of illness treatment. Bioelectronic medicine can produce, suppress, and measure electrical activity in excitable tissue. Bioelectronic devices modify specific neural circuits using electrons rather than pharmaceuticals and uses of bioelectronic processes to regulate the biological processes underlining various diseases. This promotes the potential to address the underlying causes of illnesses, reduce adverse effects, and lower costs compared to conventional medication. The current review presents different important aspects of bioelectronic medicines with recent advancements. The area of bioelectronic medicine has a lot of potential for treating diseases, enabling non-invasive therapeutic intervention by regulating brain impulses. Bioelectronic medicine uses electricity to control biological processes, treat illnesses, or regain lost capability. These new classes of medicines are designed by the technological developments in the detection and regulation of electrical signaling methods in the nervous system. Peripheral nervous system regulates a wide range of processes in chronic diseases; it involves implanting small devices onto specific peripheral nerves, which read and regulate the brain signaling patterns to achieve therapeutic effects specific to the signal capacity of a particular organ. The potential for bioelectronic medicine field is vast, as it investigates for treatment of various diseases, including rheumatoid arthritis, diabetes, hypertension, paralysis, chronic illnesses, blindness, etc.
生物电子医学是一个多学科领域,它将分子医学、神经科学、工程学和计算机科学结合起来,设计用于诊断和治疗疾病的设备。生物电子医学的进步可以提高疾病治疗的精确性和个性化。生物电子医学可以产生、抑制和测量可兴奋组织的电活动。生物电子设备使用电子而不是药物来修改特定的神经回路,并利用生物电子过程来调节各种疾病背后的生物过程。这有助于解决疾病的根本原因,减少不良反应,并降低与传统药物相比的成本。本综述介绍了生物电子医学的不同重要方面及其最新进展。生物电子医学领域在治疗疾病方面有很大的潜力,可以通过调节大脑脉冲来实现非侵入性的治疗干预。生物电子医学使用电流来控制生物过程、治疗疾病或恢复失去的功能。这些新型药物是通过检测和调节神经系统电信号方法的技术发展设计的。周围神经系统调节慢性疾病中的多种过程;它涉及将小型设备植入特定的周围神经,以读取和调节大脑信号模式,从而实现针对特定器官信号能力的治疗效果。生物电子医学领域的潜力是巨大的,因为它可以治疗各种疾病,包括类风湿关节炎、糖尿病、高血压、瘫痪、慢性疾病、失明等。