咽部给氧装置维持人体模型肺部氧合的时间比高流量鼻导管更长。
Pharyngeal oxygen delivery device sustains manikin lung oxygenation longer than high-flow nasal cannula.
作者信息
Hanson Jeramie B, Williams John R, Garmon Emily H, Morris Phillip M, McAllister Russell K, Shaver Courtney N, Culp William C
机构信息
Baylor Scott & White Medical Center - Temple, Temple, Texas, USA.
Texas A&M School of Medicine, Temple, Texas, USA.
出版信息
Proc (Bayl Univ Med Cent). 2023 Dec 20;37(1):48-53. doi: 10.1080/08998280.2023.2274702. eCollection 2024.
PURPOSE
Hypoxemia during a failed airway scenario is life threatening. A dual-lumen pharyngeal oxygen delivery device (PODD) was developed to fit inside a traditional oropharyngeal airway for undisrupted supraglottic oxygenation and gas analysis during laryngoscopy and intubation. We hypothesized that the PODD would provide oxygen as effectively as high-flow nasal cannula (HFNC) while using lower oxygen flow rates.
METHODS
We compared oxygen delivery of the PODD to HFNC in a preoxygenated, apneic manikin lung that approximated an adult functional residual capacity. Four arms were studied: HFNC at 20 and 60 liters per minute (LPM) oxygen, PODD at 10 LPM oxygen, and a control arm with no oxygen flow after initial preoxygenation. Five randomized 20-minute trials were performed for each arm (20 trials total). Descriptive statistics and analysis of variance were used with statistical significance of < 0.05.
RESULTS
Mean oxygen concentrations were statistically different and decreased from 97% as follows: 41 ± 0% for the control, 90 ± 1% for HFNC at 20 LPM, 88 ± 2% for HFNC at 60 LPM, and 97 ± 1% (no change) for the PODD at 10 LPM.
CONCLUSION
Oxygen delivery with the PODD maintained oxygen concentration longer than HFNC in this manikin model at lower flow rates than HFNC.
目的
气道管理失败时的低氧血症会危及生命。我们研发了一种双腔咽式给氧装置（PODD），它可适配于传统口咽气道内，以便在喉镜检查和插管过程中实现声门上不间断给氧及气体分析。我们假设，PODD在较低氧流量条件下，能与高流量鼻导管（HFNC）一样有效地提供氧气。
方法
在一个预先充氧、模拟成人体功能残气量的无呼吸人体模型肺上，我们比较了PODD与HFNC的给氧情况。研究分为四组：HFNC分别以每分钟20升和60升（LPM）的氧流量给氧、PODD以每分钟10升的氧流量给氧，以及一个初始预充氧后无氧气流量的对照组。每组进行5次随机的20分钟试验（共20次试验）。采用描述性统计和方差分析，统计学显著性设定为<0.05。
结果
平均氧浓度在统计学上存在差异，从97%开始下降，具体如下：对照组为41±0%，HFNC以20 LPM给氧时为90±1%，HFNC以60 LPM给氧时为88±2%，PODD以10 LPM给氧时为97±1%（无变化）。
结论
在此人体模型中，PODD在较低流量下比HFNC能更长时间地维持氧浓度。
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