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胆固醇随衰老的变化:其本质及意义。

Cholesterol changes with aging: their nature and significance.

作者信息

Kasim S

出版信息

Geriatrics. 1987 Mar;42(3):73-6, 79-82.

PMID:3817481
Abstract

Aging is associated with progressive increases in plasma triglyceride, total cholesterol, and high-density lipoprotein cholesterol levels. In the general population, total cholesterol correlates directly and high-density lipoprotein cholesterol correlates inversely with the risk of coronary artery disease. In the elderly, similar correlations between serum lipids and coronary risk also exist but are less powerful than in younger subjects. The mechanisms of the plasma lipid alterations and the current guidelines for their management in the elderly are presented.

摘要

衰老与血浆甘油三酯、总胆固醇和高密度脂蛋白胆固醇水平的逐渐升高有关。在一般人群中,总胆固醇与冠状动脉疾病风险直接相关,而高密度脂蛋白胆固醇与冠状动脉疾病风险呈负相关。在老年人中,血脂与冠心病风险之间也存在类似的相关性,但不如年轻受试者明显。本文介绍了老年人血浆脂质改变的机制及其当前的管理指南。

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