Shaik Khaja Moinuddin, Patibandla Vijay, Nandi Sukhendu
Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, 160062, Punjab, India.
Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, 160062, Punjab, India.
Steroids. 2024 Mar;203:109361. doi: 10.1016/j.steroids.2023.109361. Epub 2024 Jan 3.
In the wake of the Novel Coronavirus arrival, the world witnessed the fragility of healthcare systems and the resilience of healthcare workers who stood on the front lines. SARS-CoV-2, also known as COVID-19 or severe acute respiratory syndrome, first appeared in China in December 2019. The infection quickly spread across the nation and the world. All countries severely restricted social interaction to stop the virus's transmission, impacting all sporting, social, and recreational activities. Anabolic androgenic steroids (AASs) are frequently used illegally to enhance strength and physical attractiveness. However, they could hurt immune system health. Much research hasn't been done yet on the connection between Covid-19 and AASs. Synthetic testosterone analogs known as anabolic androgenic steroids (AASs) can have an immune-system-altering effect. Sportspeople and bodybuilders are vulnerable to AAS abuse. Governmental reactions to the coronavirus infection issue over the last year have drawn much attention and discussion regarding public services, the experience and lessons learned from different limitations, and strategies for dealing with potential future pandemics. Using AAS has the potential to cause a variety of adverse reactions, including cardiovascular issues (including high blood pressure, heart disease, and blood clots), liver damage, renal failure, mood swings, aggressiveness, and psychiatric disorders. Individuals already suffering from severe respiratory conditions like COVID-19 may have these risks increased. This review mainly highlights the anabolic androgen steroids use and its unseen effects on coronavirus patients and gymnastics.
新型冠状病毒出现后,全世界目睹了医疗系统的脆弱性以及站在前线的医护人员的韧性。严重急性呼吸综合征冠状病毒2(SARS-CoV-2),也被称为新冠病毒19或严重急性呼吸综合征,于2019年12月首次在中国出现。感染迅速在全国乃至全球蔓延。所有国家都严格限制社交互动以阻止病毒传播,这影响了所有体育、社交和娱乐活动。合成代谢雄激素类固醇(AASs)经常被非法用于增强力量和身体吸引力。然而,它们可能会损害免疫系统健康。关于新冠病毒19与AASs之间的联系,目前尚未进行大量研究。被称为合成代谢雄激素类固醇(AASs)的合成睾酮类似物可能会产生改变免疫系统的作用。运动员和健美运动员容易滥用AASs。过去一年政府对冠状病毒感染问题的反应引发了人们对公共服务、从不同限制措施中吸取的经验教训以及应对未来潜在大流行策略的诸多关注和讨论。使用AASs有可能引发多种不良反应,包括心血管问题(如高血压、心脏病和血栓)、肝损伤、肾衰竭、情绪波动、攻击性和精神障碍。已经患有像新冠病毒19这样严重呼吸道疾病的个体,这些风险可能会增加。本综述主要强调合成代谢雄激素类固醇的使用及其对冠状病毒患者和体操运动员的潜在影响。