Department of Ophthalmology, Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Experimental Center, Shandong Academy of Eye Disease Prevention and Therapy, Jinan, China.
Cornea. 2024 Mar 1;43(3):394-397. doi: 10.1097/ICO.0000000000003453. Epub 2024 Jan 5.
Multimodal imaging was performed to characterize butterfly hair-induced keratitis based on anterior segment optical coherence tomography and in vivo confocal microscopy.
This study was a case report.
A 6-year-old girl presented with acute keratitis induced by multiple butterfly hairs. Severe itching and pain developed immediately after rubbing her left eye, leading to significant pain and moderate vision loss, even after undergoing twice removal of the corneal epithelium. The hair-like foreign bodies were distributed at various depths inside the corneal stroma, even extending into the anterior chamber. The symptoms and corneal infiltration gradually decreased within 6 months with the use of topical steroids and immunosuppressors. The hairs located in the superficial and middle stromal layers of the cornea disappeared at the 6-month follow-up, but the hairs in the deep stromal layer tended to move deeper. The diagnosis was confirmed by in vivo confocal microscopy and microphotography. The migration tendency of the hairs into the intraocular space was observed using anterior segment optical coherence tomography (AS-OCT).
Butterfly hair-induced keratitis can be controlled by the treatment with topical steroids and immunosuppressors, but the hairs tend to move into the eyes. To the best of our knowledge, this is the first case of corneal in vivo confocal imaging of butterfly hairs.
通过眼前节光学相干断层扫描和活体共聚焦显微镜对蝴蝶毛引起的角膜炎进行多模态成像，以对其进行特征描述。
这是一项病例报告。
一名 6 岁女孩因多根蝴蝶毛导致急性角膜炎。左眼揉搓后立即出现剧烈瘙痒和疼痛，导致明显疼痛和中度视力丧失，甚至在两次角膜上皮去除后仍如此。毛发状异物分布在角膜基质的不同深度，甚至延伸到前房。在使用局部类固醇和免疫抑制剂 6 个月内，症状和角膜浸润逐渐减轻。角膜浅层和中层的毛发在 6 个月随访时消失，但深层基质层的毛发有向深部移动的趋势。通过活体共聚焦显微镜和显微镜摄影确诊。使用眼前节光学相干断层扫描（AS-OCT）观察毛发向眼内空间迁移的趋势。
蝴蝶毛引起的角膜炎可以通过局部类固醇和免疫抑制剂治疗得到控制，但毛发有向眼内移动的趋势。据我们所知，这是首例蝴蝶毛的角膜共聚焦活体成像病例。
