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阳离子交换树脂(聚苯乙烯磺酸钠)作为百草枯吸附剂的有效性:实验与临床研究

The effectiveness of a cation resin (Kayexalate) as an adsorbent of paraquat: experimental and clinical studies.

作者信息

Yamashita M, Naito H, Takagi S

出版信息

Hum Toxicol. 1987 Jan;6(1):89-90. doi: 10.1177/096032718700600115.

Abstract

The cation-exchange-resin Kayexalate has an adsorption capacity for paraquat 15 times greater than activated charcoal and 6 times greater than Adsorbin. The oral LD50 of paraquat in rats rose 2.1 times by intragastric injection of Kayexalate. In the present study, the survival rate of rats given Kayexalate or Adsorbin after paraquat administration was examined. Results of clinical studies on 22 patients are also presented.

摘要

阳离子交换树脂降钾树脂对百草枯的吸附能力比对活性炭大15倍,比对吸附树脂大6倍。大鼠经口给予百草枯后,通过胃内注射降钾树脂,其半数致死量提高了2.1倍。在本研究中,检测了给予百草枯后再给予降钾树脂或吸附树脂的大鼠的存活率。还展示了对22名患者的临床研究结果。

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