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经皮椎间孔入路单侧双通道内镜下治疗椎间孔外型腰椎间盘突出症:一项回顾性观察性研究。

Transforaminal Unilateral Biportal Endoscopic Spinal Surgery for Extraforaminal Lumbar Disc Herniation: A Retrospective Observational Study.

机构信息

Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; Department of Neurosurgery, China Medical University Hsinchu Hospital, China Medical University, Hsinchu, Taiwan; Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan.

Department of Neurosurgery, China Medical University Hsinchu Hospital, China Medical University, Hsinchu, Taiwan.

出版信息

World Neurosurg. 2024 Mar;183:e658-e667. doi: 10.1016/j.wneu.2023.12.162. Epub 2024 Jan 3.

Abstract

OBJECTIVE

Biportal endoscopic spinal surgery (BESS) is recommended as a safer and less destructive option for lumbar disc herniations. However, limited data exist on clinical outcomes for extraforaminal lumbar disc herniation (ELDH) surgery. This retrospective study presents our preliminary experience with transforaminal unilateral BESS for ELDH.

METHODS

Patients with lumbar radiculopathy refractory to conservative treatment, diagnosed with ELDH by magnetic resonance imaging, and treated with transforaminal unilateral BESS in 2021-2023 in 2 institutions in Taiwan were eligible for inclusion. Those with lumbar spondylolisthesis grade 2 or more with segmental instability, history of drug abuse or psychiatric diseases, or with a follow-up duration <1 year were excluded. Primary outcomes included visual analog scale for pain, assessed at 1 week, 1 month, 6 months, and 1 year using generalized estimating equations analysis; success and satisfaction of BESS graded by the Macnab criteria; and perioperative complications. Secondary outcomes were operative time and hospital length of stay.

RESULTS

Seventeen patients were included in the analysis, with a mean age of 65.8 years; 11 (64.7%) were males and 15 (88.2%) had no prior lumbar spine surgery. mean operative time was 107.9 minutes, and length of stay was 3.5 days. Graded by Macnab criteria, 16 (94.1%) of patients had good to excellent outcomes. Only 1 patient experienced complications. No recurrence/reoperation was observed. Generalized estimating equations analysis showed that postoperative visual analog scale scores decreased significantly at 1 week (adjusted Beta [aBeta] = -5.47, standard error: 0.29, P < 0.001), 1 month (aBeta = -5.82), 6 months (aBeta = -5.88), and 1 year (aBeta = -6.29).

CONCLUSIONS

Transforaminal unilateral BESS is an alternative and feasible method for treating ELDH, producing good surgical outcomes with few complications and sustaining pain improvement. Future studies with larger patient numbers and comparisons between BESS and other minimally invasive techniques for ELDH are warranted.

摘要

目的

双端口内窥镜脊柱手术(BESS)被推荐为治疗腰椎间盘突出症更安全、破坏性更小的选择。然而,对于椎间孔外腰椎间盘突出症(ELDH)手术的临床结果数据有限。本回顾性研究介绍了我们在 2021 年至 2023 年在台湾的 2 家机构使用经椎间孔单侧 BESS 治疗 ELDH 的初步经验。符合以下条件的患者有资格入选:经磁共振成像诊断为 ELDH 且对保守治疗无反应,接受经椎间孔单侧 BESS 治疗;腰椎滑脱 2 级或以上伴节段不稳定、药物滥用或精神疾病史或随访时间<1 年的患者除外。主要结局包括使用广义估计方程分析在 1 周、1 个月、6 个月和 1 年时疼痛的视觉模拟评分;Macnab 标准评定的 BESS 成功率和满意度;以及围手术期并发症。次要结局为手术时间和住院时间。

结果

共纳入 17 例患者进行分析,平均年龄 65.8 岁;11 例(64.7%)为男性,15 例(88.2%)无腰椎手术史。平均手术时间为 107.9 分钟,住院时间为 3.5 天。根据 Macnab 标准分级,16 例(94.1%)患者的疗效为良好至优秀。仅 1 例患者发生并发症。无复发或再次手术。广义估计方程分析显示,术后视觉模拟评分在 1 周(调整后 Beta[aBeta]=-5.47,标准误差:0.29,P<0.001)、1 个月(aBeta=-5.82)、6 个月(aBeta=-5.88)和 1 年(aBeta=-6.29)时显著下降。

结论

经椎间孔单侧 BESS 是治疗 ELDH 的一种替代方法,具有可行性,并发症少,能持续缓解疼痛,取得良好的手术效果。未来需要更大样本量的研究,并对 BESS 与其他 ELDH 微创技术进行比较。

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