Liao Zi-Kun, Xia Shu-Yang, Li Qun, Zhou Wei, Zhang Ping
Guangzhou Medical University, Guangzhou, Guangdong, China.
Anhui Medical University, Hefei, Anhui, China.
Med Sci Monit. 2024 Dec 14;30:e946468. doi: 10.12659/MSM.946468.
BACKGROUND Lumbar degenerative diseases, such as lumbar disc herniation, cause significant pain and neurological deficits. Traditional surgeries like posteriior lumbar interbody fusion (PLIF) have drawbacks, including extensive tissue damage. We sought to evaluate the efficacy of unilateral biportal endoscopy (UBE) compared with PLIF, with a focus on clinical outcomes and complication rates. MATERIAL AND METHODS This retrospective study (January 2020 to January 2023) included 109 patients with lumbar degenerative diseases; 53 treated with UBE and 56 with PLIF. We followed Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines with ethical approval. The statistical analyses used t-tests and Chi-square tests (P<0.05). RESULTS The UBE group showed significantly shorter surgery times (107.3±11.2 minutes) and less intraoperative blood loss (50.2±5.7 mL) compared with the PLIF group (113.5±15.7 minutes; 91.3±9.0 mL). Postoperative pain reduction was greater in the UBE group, with a mean Visual Analogue Scale (VAS) score of 3.50±0.85 vs 4.10±0.95 in the PLIF group (P<0.001). The UBE group also had better lumbar function recovery, with higher Japanese Orthopaedic Association scores (19.80±2.30 vs 17.20±2.05; P<0.001). The incidence of postoperative complications was lower in the UBE group (5.67%) compared with the PLIF group (14.29%), although this difference was not statistically significant (P=0.14). CONCLUSIONS UBE could offer significant clinical efficacy in treating lumbar degenerative diseases. It may improve surgical outcomes, reduce postoperative pain, and present a favorable safety profile. These findings suggest UBE might be a viable, minimally invasive option, promoting better recovery and fewer complications.
背景 腰椎退行性疾病,如腰椎间盘突出症,会导致严重疼痛和神经功能缺损。像后路腰椎椎间融合术(PLIF)这样的传统手术存在缺点,包括广泛的组织损伤。我们试图评估单侧双通道内镜手术(UBE)与PLIF相比的疗效,重点关注临床结果和并发症发生率。
材料与方法 这项回顾性研究(2020年1月至2023年1月)纳入了109例腰椎退行性疾病患者;53例接受UBE治疗,56例接受PLIF治疗。我们遵循加强流行病学观察性研究报告(STROBE)指南并获得伦理批准。统计分析采用t检验和卡方检验(P<0.05)。
结果 与PLIF组(113.5±15.7分钟;91.3±9.0毫升)相比,UBE组的手术时间明显更短(107.3±11.2分钟),术中出血量更少(50.2±5.7毫升)。UBE组术后疼痛减轻更明显,平均视觉模拟评分(VAS)为3.50±0.85,而PLIF组为4.10±0.95(P<0.001)。UBE组的腰椎功能恢复也更好,日本骨科协会评分更高(19.80±2.30对17.20±2.05;P<0.001)。UBE组术后并发症发生率(5.67%)低于PLIF组(14.29%),尽管这一差异无统计学意义(P=0.14)。
结论 UBE在治疗腰椎退行性疾病方面可提供显著的临床疗效。它可能改善手术效果,减轻术后疼痛,并具有良好的安全性。这些发现表明UBE可能是一种可行的微创选择,能促进更好的恢复且并发症更少。