Hervás J A, Masip M C, Alomar A, Bregante J I
Helv Paediatr Acta. 1986 Dec;41(5):437-40.
A female premature infant born after 27-week gestation developed a localized perforation of the terminal ileum six days after the administration of intravenous indomethacin for PDA closure. This complication has been reported after enteral and rectal administration of the drug. However, our clinical finding supports that these lesions in premature infants are not only related to the local effects of enteral indomethacin.
一名孕27周出生的女早产儿在静脉注射吲哚美辛以关闭动脉导管未闭六天后，出现了回肠末端局限性穿孔。在经肠内和直肠给药该药物后曾有此并发症的报道。然而，我们的临床发现表明，早产儿的这些病变不仅与肠内吲哚美辛的局部作用有关。
