Department of Pharmaceutics, College of Pharmacy, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia.
Int J Biol Macromol. 2024 Mar;260(Pt 1):129215. doi: 10.1016/j.ijbiomac.2024.129215. Epub 2024 Jan 6.
In the last ten years, remarkable characteristics and a variety of functionalities have been created in biopolymeric materials for clinical dental applications. This review gives an overview of current knowledge of natural biopolymers (biological macromolecules) in terms of structural, functional, and property interactions. Natural biopolymers such as polysaccharides (chitosan, bacterial cellulose, hyaluronic acid, and alginate) and polypeptides (collagen and silk fibroin) have been discussed for dental uses. These biopolymers exhibit excellent properties alone and when employed with other composite molecules making them ideal for treatment of periodontitis, endodontics, dental pulp regeneration and oral wound healing. These biopolymers together with the composite materials exhibit better biocompatibility, inertness, elasticity and flexibility which makes them a leading candidate to be used for other dental applications like caries management, oral appliances, dentures, dental implants and oral surgeries.
在过去的十年中，生物聚合材料在临床牙科应用中展现出了显著的特点和多样化的功能。本综述概述了天然生物聚合物（生物大分子）在结构、功能和性能相互作用方面的现有知识。本文讨论了用于牙科用途的天然生物聚合物，如多糖（壳聚糖、细菌纤维素、透明质酸和藻酸盐）和多肽（胶原和丝素蛋白）。这些生物聚合物单独使用时具有优异的性能，与其他复合分子一起使用时，它们是治疗牙周炎、牙髓再生和口腔伤口愈合的理想选择。这些生物聚合物与复合材料一起具有更好的生物相容性、惰性、弹性和柔韧性，这使得它们成为用于其他牙科应用的首选材料，如龋齿管理、口腔器具、义齿、牙种植体和口腔手术。
