Siddig Khulood A, Nazhat Omar M, Saleem Nadia M, Hamadi Iyad S, AlHashimi Fatma A
Department of Otorhinolaryngology, Dubai Academic Health Corporation, Dubai, ARE.
Department of Otorhinolaryngology, Dubai Hospital, Dubai, ARE.
Cureus. 2023 Dec 8;15(12):e50172. doi: 10.7759/cureus.50172. eCollection 2023 Dec.
Schwannomas are relatively slow-growing benign tumors of the nerve sheath. Approximately 25-40% of schwannomas occur in the head and neck region. However, schwannomas that present in the oral cavity are relatively rare, constituting around 1% of all described cases in the head and neck region. We report a case of a 20-year-old female who was found to have an intraoral palatal schwannoma. The patient presented with a painless swelling located on the right side of the soft palate. Investigations and management were commenced, and a computed tomography (CT) scan with contrast was done, which revealed cystic changes in a large soft palate mass lesion with a heterogeneous enhancement. The mass was surgically excised and sent for histopathological examination. The diagnosis of schwannoma was made due to the presence of the characteristic Antoni A and Antoni B areas. The immunohistochemical study done was positive for protein S-100. The postoperative follow-up went uneventful.
神经鞘瘤是神经鞘相对生长缓慢的良性肿瘤。约25% - 40%的神经鞘瘤发生在头颈部区域。然而，口腔内出现的神经鞘瘤相对罕见，约占头颈部区域所有已描述病例的1%。我们报告一例20岁女性，发现患有口腔内腭部神经鞘瘤。患者表现为软腭右侧无痛性肿胀。开始进行检查和处理，进行了增强计算机断层扫描（CT），结果显示一个大的软腭肿块病变有囊性改变，增强不均匀。该肿块经手术切除并送去做组织病理学检查。由于存在特征性的Antoni A区和Antoni B区，诊断为神经鞘瘤。所做的免疫组织化学研究显示蛋白S - 100呈阳性。术后随访情况良好。
