Alrehaili Ruba A, ElKady Reem M, Alrehaili Jumana A, Alreefi Reem M
Family Medicine, Academy of Family Medicine, Ministry of Health, Al-Madinah, SAU.
Radiology and Medical Imaging, Faculty of Medicine, Taibah University, Al-Madinah, SAU.
Cureus. 2023 Dec 7;15(12):e50111. doi: 10.7759/cureus.50111. eCollection 2023 Dec.
Autism spectrum disorders (ASD) encompass a diverse range of developmental disabilities characterized by pervasive deficiencies in socialization, communication, and the manifestation of behavioral issues. This review aims to clarify the diagnostic criteria for ASD, explore available diagnostic tools, evaluate biomedical examinations facilitating ASD diagnosis, and discuss the approach to screening assessments for ASD. ASDs are prevalent conditions, with a globally estimated prevalence of 7.6 cases per 100 (one in 132), based on a comprehensive review of epidemiological studies. The precise cause of autism and other ASDs remains unknown; however, genetic and environmental factors likely contribute. Common signs and symptoms shared among individuals with autism include restricted repetitive behaviors and learning disabilities. Standardized methods, such as the Diagnostic and Statistical Manual, Fifth Edition (DSM-5), diagnostic instruments, a thorough medical history, multiple physical examinations, laboratory investigations, neuroimaging, and screening tests, play a pivotal role in early autism diagnosis and intervention. ASD is a lifelong neurodevelopmental condition characterized by multiple deficits. Early detection is anticipated to have a positive impact on outcomes.
自闭症谱系障碍(ASD)涵盖了一系列不同的发育障碍,其特征是在社交、沟通以及行为问题表现方面普遍存在缺陷。本综述旨在阐明ASD的诊断标准,探索可用的诊断工具,评估有助于ASD诊断的生物医学检查,并讨论ASD筛查评估的方法。ASD是一种普遍存在的疾病,根据对流行病学研究的全面综述,全球估计患病率为每100人中有7.6例(132人中1例)。自闭症和其他ASD的确切病因尚不清楚;然而,遗传和环境因素可能起作用。自闭症患者共有的常见体征和症状包括受限的重复行为和学习障碍。标准化方法,如《精神疾病诊断与统计手册》第五版(DSM-5)、诊断工具、详尽的病史、多次体格检查、实验室检查、神经影像学检查和筛查测试,在自闭症的早期诊断和干预中起着关键作用。ASD是一种以多种缺陷为特征的终身神经发育疾病。早期发现预计会对结果产生积极影响。