Landin L A, Danielsson L G, Wattsgård C
J Bone Joint Surg Br. 1987 Mar;69(2):238-42. doi: 10.1302/0301-620X.69B2.3818754.
In a prospective five-year study, 294 episodes of acute transient synovitis of the hip were diagnosed in 275 children. The average annual incidence was 0.2% and the accumulated risk of suffering at least one episode was 3%. The risk of recurrence was 20 times greater than the risk of having a single episode. Perthes' disease was diagnosed from one to five months after the acute attack of synovitis in 10 cases (3.4%). Review of the initial radiographs revealed signs of avascular necrosis in three of the 10 cases, and an increased joint space in five. Only two cases had had completely normal radiographs. The value of routine radiographs taken after three months was minimal. Factors associated with the incidence of Perthes' disease included prolonged time in traction before the range of hip movement became normal, increase in joint space on the initial radiographs and the recurrence of hip symptoms after initial relief.
在一项为期五年的前瞻性研究中，275名儿童被诊断出294例急性暂时性髋滑膜炎。年平均发病率为0.2%，至少发生一次该病的累积风险为3%。复发风险比单次发病风险高20倍。10例（3.4%）患者在滑膜炎急性发作后1至5个月被诊断为佩特兹病。回顾最初的X线片发现，10例中有3例有缺血性坏死迹象，5例关节间隙增宽。只有2例最初的X线片完全正常。三个月后进行的常规X线片检查价值极小。与佩特兹病发病率相关的因素包括在髋关节活动范围恢复正常之前牵引时间延长、最初X线片上关节间隙增宽以及最初症状缓解后髋部症状复发。
