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转向用于紧张症的加速重复经颅磁刺激方案:一例报告

Moving to accelerated protocols of tDCS in catatonia: a case report.

作者信息

Bouaziz Noomane, Luisada Jean-Charles, Jabri Samir, Andrianisaina Palmyre S-K, Bellis Avicenne, Januel Dominique

机构信息

Hôpital de Ville-Évrard, Neuilly-sur-Marne, France.

出版信息

Front Psychiatry. 2023 Dec 21;14:1302718. doi: 10.3389/fpsyt.2023.1302718. eCollection 2023.

Abstract

Catatonia is a severe and potentially life-threatening neuropsychiatric condition. Electroconvulsive therapy (ECT) is the gold standard second-line intervention for catatonia after benzodiazepine failure. However, the access to ECT can be particularly challenging, especially during periods of increased strain on medical facilities, such as the COVID-19 pandemic. Several case reports have suggested the potential efficacy of transcranial direct current stimulation (tDCS) in addressing catatonia. In our case, we present the successful application of intensive tDCS, delivering five sessions per day, each lasting 20 min, with an intensity of 2 mA. The tDCS montage involved placing the anode on the left dorsolateral prefrontal cortex (DLPFC) and the cathode on the left temporoparietal junction (TPJ). This approach was well-tolerated and resulted in a significant improvement in a 70-year-old patient with catatonia, for whom ECT was deemed necessary. While these results are promising, it is crucial to confirm them through a randomized controlled study.

摘要

紧张症是一种严重且可能危及生命的神经精神疾病。电休克疗法(ECT)是苯二氮䓬类药物治疗失败后治疗紧张症的金标准二线干预措施。然而,ECT的获取可能特别具有挑战性,尤其是在医疗设施压力增加的时期,如新冠疫情期间。一些病例报告表明经颅直流电刺激(tDCS)在治疗紧张症方面可能有效。在我们的病例中,我们展示了强化tDCS的成功应用,每天进行5次治疗,每次持续20分钟,强度为2毫安。tDCS的电极放置方式是将阳极置于左侧背外侧前额叶皮质(DLPFC),阴极置于左侧颞顶叶交界处(TPJ)。这种方法耐受性良好,并使一名70岁的紧张症患者有显著改善,该患者被认为需要进行ECT治疗。虽然这些结果很有前景,但通过随机对照研究来证实它们至关重要。

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本文引用的文献

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