Wathes D C, Wardle P G, Rees J M, Mitchell J D, McLaughlin E A, Hull M G, Porter D G
Hum Reprod. 1986 Dec;1(8):515-7. doi: 10.1093/oxfordjournals.humrep.a136465.
Relaxin immunoreactivity has been found in samples of human follicular fluid collected from artificially stimulated pre-ovulatory follicles. The crude extract caused a reduction in the height of the contractions in a rat uterine strip bioassay. The reactive material eluted from Sephadex G50 in two major peaks. The first contained approximately 60% of the immunoreactivity and had an elution position corresponding to that of porcine relaxin, indicating a mol. wt of approximately 6000 daltons. The second peak was of a lower mol. wt, but its exact size and significance are unknown. A possible role for relaxin in the process of follicular rupture is suggested.
在从人工刺激的排卵前卵泡收集的人卵泡液样本中发现了松弛素免疫反应性。粗提物在大鼠子宫条生物测定中导致收缩高度降低。从葡聚糖凝胶G50洗脱的反应性物质有两个主要峰。第一个峰含有约60%的免疫反应性，其洗脱位置与猪松弛素的洗脱位置相对应，表明分子量约为6000道尔顿。第二个峰的分子量较低，但其确切大小和意义尚不清楚。提示松弛素在卵泡破裂过程中可能起作用。
