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患者对 Mepitel Film 预防乳腺癌急性放射性皮炎的使用体验。

Patient-reported experience with the use of Mepitel Film for prevention of acute radiation dermatitis in breast cancer.

机构信息

Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

Department of Radiation Therapy, University of Otago, Wellington, New Zealand.

出版信息

Support Care Cancer. 2024 Jan 8;32(1):89. doi: 10.1007/s00520-023-08302-4.

DOI:10.1007/s00520-023-08302-4
PMID:38190084
Abstract

BACKGROUND AND PURPOSE

Mepitel Film (MF) has been demonstrated to reduce the severity of radiation dermatitis (RD) in patients receiving breast cancer radiotherapy (RT). The objective of this study was to characterize patient-reported experience with MF use, including its impact on daily activities and wellbeing.

MATERIALS AND METHODS

This single-institution study analyzed anonymized responses to a questionnaire completed by patients who used MF for the prevention of RD during breast cancer RT.

RESULTS

Of the 254 patients contacted, 192 patients completed the survey. Most patients disagreed or strongly disagreed that MF limited their ability to perform their daily activities, including household chores (88%, n = 169/191), their ability to work (83%, n = 157/189), or their ability to sleep (85%, n = 163/191). Furthermore, patients agreed or strongly agreed MF was comfortable on their skin (67%, n = 126/189) and protected their skin from rubbing against clothing (86%, n = 161/188). Some patients agreed or strongly agreed that MF affected their ability to shower (31%, n = 50/162), wear bras (28%, n = 51/185), and impacted their level of pruritus (35%, n = 67/189). However, most patients agreed or strongly agreed that their overall experience with MF was positive (92%, n = 173/189) and would recommend MF to a friend undergoing breast cancer RT (88%, n = 166/188).

CONCLUSION

MF use is associated with positive patient-reported experience during breast RT with minimal impact on daily activities.

摘要

背景与目的

美皮康薄膜(MF)已被证实可减轻接受乳腺癌放疗(RT)患者的放射性皮炎(RD)严重程度。本研究旨在描述患者对 MF 使用体验的报告,包括其对日常活动和生活质量的影响。

材料与方法

本单中心研究分析了使用 MF 预防乳腺癌 RT 期间 RD 的患者完成的匿名调查问卷的应答。

结果

在联系的 254 名患者中,有 192 名患者完成了调查。大多数患者表示 MF 并未限制其日常活动能力,包括家务(88%,169/191)、工作能力(83%,157/189)或睡眠能力(85%,163/191)。此外,患者表示 MF 贴在皮肤上很舒适(67%,126/189)且能防止皮肤与衣物摩擦(86%,161/188)。一些患者表示 MF 影响了其洗澡(31%,50/162)、戴胸罩(28%,51/185)和瘙痒程度(35%,67/189)的能力。然而,大多数患者对 MF 的总体体验评价积极(92%,173/189),并会向接受乳腺癌 RT 的朋友推荐 MF(88%,166/188)。

结论

MF 在乳腺癌 RT 中使用时患者的报告体验良好,对日常活动的影响极小。

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本文引用的文献

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Support Care Cancer. 2023 Nov 28;31(12):725. doi: 10.1007/s00520-023-08205-4.
2
Patients Satisfied with Care Report Better Quality of Life and Self-Rated Health-Cross-Sectional Findings Based on Hospital Quality Data.对护理感到满意的患者报告生活质量和自评健康状况更好——基于医院质量数据的横断面研究结果
Healthcare (Basel). 2023 Mar 6;11(5):775. doi: 10.3390/healthcare11050775.
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Cancer statistics, 2023.
癌症统计数据,2023 年。
CA Cancer J Clin. 2023 Jan;73(1):17-48. doi: 10.3322/caac.21763.
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Mepitel Film for the Prevention of Acute Radiation Dermatitis in Breast Cancer: A Randomized Multicenter Open-Label Phase III Trial.美皮贴预防乳腺癌急性放射性皮炎的随机多中心开放性 III 期试验。
J Clin Oncol. 2023 Feb 20;41(6):1250-1264. doi: 10.1200/JCO.22.01873. Epub 2022 Dec 9.
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A Feasibility Study of Mepitel Film for the Prevention of Breast Radiation Dermatitis in a Canadian Center.加拿大中心一项关于美皮贴薄膜预防乳腺癌放射性皮炎的可行性研究。
Pract Radiat Oncol. 2021 Jan-Feb;11(1):e36-e45. doi: 10.1016/j.prro.2020.09.004. Epub 2020 Sep 17.
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Mepitel Film is superior to Biafine cream in managing acute radiation-induced skin reactions in head and neck cancer patients: a randomised intra-patient controlled clinical trial.美皮康薄膜在管理头颈部癌症患者急性放射性皮肤反应方面优于比亚芬乳膏:一项随机患者内对照临床试验。
J Med Radiat Sci. 2020 Sep;67(3):208-216. doi: 10.1002/jmrs.397. Epub 2020 May 31.
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Breast cancer patients report reduced sensitivity and pain using a barrier film during radiotherapy - A Danish intra-patient randomized multicentre study.乳腺癌患者报告在放疗期间使用阻隔膜可降低敏感性和疼痛——一项丹麦患者内随机多中心研究。
Tech Innov Patient Support Radiat Oncol. 2018 Jun 19;7:20-25. doi: 10.1016/j.tipsro.2018.05.004. eCollection 2018 Sep.
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Int J Dermatol. 2017 Sep;56(9):909-914. doi: 10.1111/ijd.13371. Epub 2016 Aug 6.
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