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美国老年人饮酒与抑郁症状评分之间的双向关联。

Bidirectional associations between alcohol drinking and depressive symptom scores among US older adults.

作者信息

Yu Xinhua, Gain Easter P, Kedia Satish K

机构信息

Division of Epidemiology, Biostatistics and Environmental Health, School of Public Health, University of Memphis, United States of America.

Division of Epidemiology, Biostatistics and Environmental Health, School of Public Health, University of Memphis, United States of America.

出版信息

J Affect Disord. 2024 Mar 15;349:48-53. doi: 10.1016/j.jad.2024.01.004. Epub 2024 Jan 7.

Abstract

BACKGROUND

This study examines the bidirectional associations between alcohol drinking and depression in which low to moderate alcohol drinking may reduce the risk of depression, while the occurrence of depression may increase the amount of alcohol drinking as a coping strategy.

METHOD

Data for the community-dwelling older adults from the Medicare Current Beneficiary Survey (MCBS) 2016 to 2019 were analyzed using random intercept cross-lagged panel models to explore the within-individual causal associations for males and females separately. Socioeconomic status (SES), smoking and comorbidities were adjusted in the models.

RESULTS

Among 3388 older adults with three measures for the number of alcohol drinks and Patient Health Questionnaire (PHQ) depression scores, a prior increase in the number of drinks was related to a moderate non-significant decrease in PHQ scores in the follow-up, but a previous increase in the PHQ scores was significantly associated with a decrease in the number of drinks at the follow-up visit in the adjusted models (regression coefficient = -0.144, p = 0.017 for males; and coefficient = -0.11, p < 0.001 for females).

CONCLUSION

Prior depression may lead to reduced drinking in the follow up visits, but no bidirectional association was found among US older adults.

摘要

背景

本研究探讨饮酒与抑郁症之间的双向关联,即低度至中度饮酒可能降低患抑郁症的风险,而抑郁症的发生可能会增加饮酒量作为一种应对策略。

方法

使用随机截距交叉滞后面板模型分析了2016年至2019年医疗保险当前受益人调查(MCBS)中社区居住的老年人的数据,以分别探讨男性和女性个体内部的因果关联。模型中对社会经济地位(SES)、吸烟和合并症进行了调整。

结果

在3388名有三项饮酒量测量指标和患者健康问卷(PHQ)抑郁评分的老年人中,先前饮酒量的增加与随访中PHQ评分的适度非显著降低有关,但在调整模型中,先前PHQ评分的增加与随访时饮酒量的减少显著相关(男性回归系数=-0.144,p=0.017;女性系数=-0.11,p<0.001)。

结论

先前的抑郁症可能导致随访中饮酒量减少,但在美国老年人中未发现双向关联。

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