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子宫移植与生育力保存:癌症幸存者的希望曙光。

Uterine Transplantation and Fertility Preservation: A Hopeful Horizon for Cancer Survivors.

作者信息

Dewani Deepika, Karwade Pravin, Mahajan Kalyani S

机构信息

Obstetrics and Gynecology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

Obstetrics and Gynecology, Symbiosis Medical College for Women, Symbiosis International University, Pune, IND.

出版信息

Cureus. 2023 Dec 8;15(12):e50178. doi: 10.7759/cureus.50178. eCollection 2023 Dec.

Abstract

Uterine transplantation, a groundbreaking medical intervention, stands as a beacon of hope for cancer survivors grappling with the dual challenges of a cancer diagnosis and potential fertility loss due to aggressive treatments. This review provides a comprehensive exploration of uterine transplantation as an innovative solution for fertility preservation in the context of cancer survivorship. The multifaceted discussion encompasses the impact of cancer on fertility, the imperative of fertility preservation, and the evolution of uterine transplantation as a transformative procedure. The post-transplantation care section delves into the intricacies of recovery, the delicate balance of immunosuppressive therapy, and the ongoing support required for recipients to embrace the full spectrum of reproductive possibilities and overall well-being. Ethical considerations surrounding uterine transplantation, including donor selection, risk assessment, and societal perspectives, are critically examined to navigate the ethical landscape of this evolving field. In conclusion, uterine transplantation is presented as a medical breakthrough and a symbol of interdisciplinary collaboration, resilience, and unwavering hope. The review underscores the role of collaborative efforts among medical professionals, researchers, ethicists, and psychologists in advancing this transformative field. Looking to the future, uterine transplantation signifies a paradigm shift in fertility preservation, offering a tangible path toward parenthood for cancer survivors. The procedure, grounded in science, ethics, and compassion, illuminates the way forward, inspiring a future where fertility preservation becomes an attainable reality for those whose reproductive dreams were once compromised by cancer treatments.

摘要

子宫移植是一项具有开创性的医学干预措施,对于那些因癌症诊断以及积极治疗可能导致生育能力丧失而面临双重挑战的癌症幸存者来说,它是希望的灯塔。本综述全面探讨了子宫移植作为癌症幸存者生育力保存的创新解决方案。多方面的讨论涵盖了癌症对生育力的影响、生育力保存的必要性,以及子宫移植作为一种变革性手术的发展历程。移植后护理部分深入探讨了恢复的复杂性、免疫抑制治疗的微妙平衡,以及接受者为充分实现生殖可能性和整体健康所需的持续支持。对子宫移植相关伦理考量,包括供体选择、风险评估和社会观点进行了批判性审视,以应对这一不断发展领域的伦理格局。总之,子宫移植被视为一项医学突破以及跨学科合作、恢复力和坚定希望的象征。该综述强调了医学专业人员、研究人员、伦理学家和心理学家之间的合作努力在推动这一变革性领域发展中的作用。展望未来,子宫移植标志着生育力保存的范式转变,为癌症幸存者提供了一条切实可行的成为父母的道路。该手术基于科学、伦理和同情心,照亮了前进的道路,激发了一个未来,在这个未来,生育力保存对于那些生殖梦想曾因癌症治疗而受损的人来说成为一个可实现的现实。

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