Department of Medical Ethics, Philosophy and History of Medicine, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands.
Curr Opin Organ Transplant. 2023 Jun 1;28(3):192-196. doi: 10.1097/MOT.0000000000001058. Epub 2023 Feb 10.
There is no widely accepted single ethical principle for the fair allocation of scarce donor organs for transplantation. Although most allocation systems use combinations of allocation principles, there is a particular tension between 'prioritizing the worst-off' and 'maximizing total benefits'. It is often suggested that empirical research on public preferences should help solve the dilemma between equity and efficiency in allocation policy-making.
This review shows that the evidence on public preferences for allocation principles is limited, and that the normative role of public preferences in donor organ allocation policy making is unclear. The review seeks to clarify the ethical dilemma to the transplant community, and draws attention to recent attempts at balancing and rank-ordering of allocation principles.
This review suggests that policy makers should make explicit the relative weights attributed to equity and efficiency considerations in allocation policies, and monitor the effects of policy changes on important ethics outcomes, including equitable access among patient groups. Also, it draws attention to wider justice issues associated not with the distribution of donor organs among patients on waiting lists, but with barriers in referral for transplant evaluation and disparities among patient groups in access to waiting lists.
目的:目前,尚无广为接受的单一伦理原则来公平分配稀缺的供体器官进行移植。尽管大多数分配系统都使用分配原则的组合,但在“优先考虑最弱势群体”和“最大化总收益”之间存在着特殊的紧张关系。人们通常认为,关于公众偏好的实证研究应该有助于解决分配政策制定中公平与效率之间的困境。
发现:本综述表明,关于公众对分配原则的偏好的证据有限,公众偏好在供体器官分配政策制定中的规范作用尚不清楚。本综述旨在向移植界阐明这一伦理困境,并提请注意最近在平衡和排序分配原则方面的尝试。
总结:本综述表明,政策制定者应该明确在分配政策中公平和效率考虑的相对权重,并监测政策变化对重要伦理结果的影响,包括患者群体之间公平获得的机会。此外,它提请注意与等待名单上的患者之间分配供体器官相关的更广泛的正义问题,而不是与转诊进行移植评估的障碍以及患者群体在获得等待名单方面的差异有关。